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Cryopreservation of mouse thymus depletes donor thymocytes but preserves thymus function when transplanted after thawing into athymic mice. No differences in immune reconstitution were observed between fresh and frozen/thawed transplants suggesting that donor thymocyte depletion does not affect outcome. Thus, cryopreservation of thymus may improve outcomes in thymus transplant patients.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10946610 | PMC |
| http://dx.doi.org/10.1002/eji.202350546 | DOI Listing |
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