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Microbial profile of biliary tract infection in patients undergoing therapeutic endoscopic retrograde cholangiopancreatography (ERCP), and baseline risk factors predicting microbial growth and post-ERCP cholangitis.
Prz Gastroenterol
March 2024
Department of Hepato-gastroenterology, Sindh Institute of Urology and Transplantation, Karachi, Pakistan.
Introduction: Stasis of bile flow can result in microbial colonization of the biliary tree. Cholangitis is a common adverse event linked to endoscopic retrograde cholangiopancreatography (ERCP).
Aim: To establish the bacterial profiles isolated from the bile sample and to evaluate the pre-ERCP risk factors predicting the microbial growth and development of post-ERCP cholangitis (PEC).
Prospective validation and revision of predictive models for post-ERCP pancreatitis: focus on procedure-related factors and a novel risk stratification approach.
Surg Endosc
December 2024
Division of Gastroenterology, Department of Internal Medicine, Chonnam National University Hospital, Gwangju, Republic of Korea.
Introduction: Post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP) is the most common serious adverse event after endoscopic retrograde cholangiopancreatography (ERCP). Although retrospective models to predict PEP have shown promise, their real-world applicability remains uncertain. Thus, we used prospectively derived cohort data to validate current prediction models.
View Article and Find Full Text PDFPost Endoscopic Retrograde Cholangiopancreatography Pancreatitis: Novel Mechanisms and Prevention by Drugs.
United European Gastroenterol J
December 2024
Division of Gastroenterology, Department of Pediatrics, School of Medicine, Stanford University, Stanford, California, USA.
Endoscopic retrograde cholangiopancreatography (ERCP) is becoming more common than first-line therapy for pancreaticobiliary duct disorders. However, post-ERCP pancreatitis is the most common complication of ERCPs, and affects about 10% of cases. In this review, we provide an overview of the mechanisms purported to cause post-ERCP pancreatitis as well as associated risk factors.
View Article and Find Full Text PDFPredictors of Post-endoscopic Retrograde Cholangiopancreatography Pancreatitis: A Comprehensive Systematic Review and Meta-analysis.
Clin Gastroenterol Hepatol
December 2024
Division of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, Indiana.
Background & Aims: Pancreatitis is the most common serious adverse event associated with endoscopic retrograde cholangiopancreatography (ERCP). This meta-analysis aimed to precisely assess the risk factors for post-ERCP pancreatitis (PEP).
Methods: We searched electronic databases for studies that assessed risk factors for PEP after adjusting for ≥3 risk factors, including at least one pre-specified patient-related and one procedure-related risk factor, and reported the data as adjusted odds ratios (ORs) with 95% confidence intervals.
Factors Associated with the Severity of ERCP-Related Complications: A Retrospective Single-Centre Study.
J Clin Med
December 2024
Ghent University Hospital, Coupure Rechts 136, 9000 Ghent, Belgium.
Risk factors for post-endoscopic retrograde cholangiopancreatography (ERCP) complications have been extensively studied and are well established; most complications are mild and self-limiting. This study aims to identify patients at risk of severe early post-ERCP complications. We conducted a retrospective cohort study with data from 2810 ERCP procedures performed at Ghent University Hospital between 2016 and 2022.
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