AI Article Synopsis

  • The study analyzed the effects of prenatal mindfulness training (MT) compared to treatment as usual (TAU) on inflammation (measured by neutrophil-to-lymphocyte ratio or NLR) and fetal head circumference (HC%).
  • Results showed that participants in the MT group had significantly lower NLR levels during the third trimester compared to those in TAU, indicating reduced maternal inflammation.
  • While higher NLR was linked to lower fetal HC%, no significant difference in fetal HC% was found between the MT and TAU groups, suggesting more research is needed to confirm these results in a larger study.

Article Abstract

This was a secondary analysis of a prenatal mindfulness training (MT) RCT versus treatment as usual (TAU) on neutrophil-to-lymphocyte ratio (NLR), a measure of maternal inflammation, and fetal head circumference. Fifteen participants were randomized to MT and 14 to TAU. NLR in third trimester was significantly lower in the MT group ( = 7.11,  = 0.019) relative to those in TAU. Higher NLR values in second ( = -0.644,  = 0.013) and third trimesters ( = -0.601,  = 0.030) were associated with lower fetal HC%. There was no group difference in fetal HC%. A future, fully powered study is needed to replicate these findings. Clinical Trials Number: NCT03679117.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10801677PMC
http://dx.doi.org/10.1089/jicm.2023.0254DOI Listing

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