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The potential benefits of radiotherapy in elderly patients with early-stage triple-negative breast cancer.
Front Med (Lausanne)
January 2025
Department of General Surgery, The People's Hospital of Fenghua Ningbo, Ningbo, China.
Background: Breast cancer (BC) is the most common cancer in women in the U.S. and a leading cause of cancer-related deaths.
View Article and Find Full Text PDFTimber harvesting was the most important factor driving changes in vegetation composition, as compared to climate and fire regime shifts, in the mixedwood temperate forests of Temiscamingue since AD 1830.
Landsc Ecol
January 2025
Southern Swedish Forest Research Centre, Swedish University of Agricultural Sciences, Box 190, 234 22 Lomma, Sweden.
Context: The vegetation composition of northeastern North American forests has significantly changed since pre-settlement times, with a marked reduction in conifer-dominated stands, taxonomic and functional diversity. These changes have been attributed to fire regime shifts, logging, and climate change.
Methods: In this study, we disentangled the individual effects of these drivers on the forest composition in southwestern Quebec from 1830 to 2000 by conducting retrospective modelling using the LANDIS-II forest landscape model.
Extracellular matrix turnover in severe COVID-19 is reduced by corticosteroids.
Respir Res
January 2025
Department of Critical Care, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Background: Severe and critical COVID-19 is characterized by pulmonary viral infection with SARS-CoV-2 resulting in local and systemic inflammation. Dexamethasone (DEX) has been shown to improve outcomes in critically ill patients; however, its effect on tissue remodeling, particularly collagen turnover, remains unclear. This study investigated the association between circulating extracellular matrix (ECM) remodeling neo-epitopes and COVID-19 severity, their relationship with mortality, and the effect of DEX on these markers.
View Article and Find Full Text PDFQuantifying the variation patterns and environmental controls of forest litterfall: A regional synthesis of ecological data across South Korea.
Sci Total Environ
January 2025
Department of Environment and Forest Resources, College of Agriculture and Life Sciences, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon 34134, Republic of Korea. Electronic address:
Enhancing the strength of forest carbon sinks is critical in the wake of the accelerating global climate change and intensifying greenhouse effect. However, the regional patterns and environmental controls of forest litter, a major carbon pool and entry pathway from tree-to-soil systems, remain uncertain. Herein, we consolidated up to a decade of data from six ecological studies (totaling 28 stands) conducted across South Korea between 1999 and 2022 (spanning 23 years) to examine variations in total and component-based litterfall with geo-topography and climate.
View Article and Find Full Text PDFGabapentin impairs visual development in zebrafish via retinal apoptosis and thyroid disruption.
J Hazard Mater
January 2025
School of Environmental Science and Engineering, Nanjing Tech University, Jiangsu 211816, China; Sino-Portuguese Joint International Laboratory of Aquatic Toxicology, Nanjing Tech University, 30 South Puzhu Road, Nanjing, Jiangsu Province 211816, China. Electronic address:
Gabapentin (GBP), a pharmaceutical widely used for seizures and neuropathic pain, has emerged as a contaminant in global aquatic environments, raising concerns about its ecological impact. This study investigated the effects of environmentally relevant concentrations of GBP (0, 1, 10, 1000 μg/L) on visual development in zebrafish (Danio rerio). Behavioral assays showed that GBP exposure enhanced light sensitivity, as indicated by a significant increase in total travel distance (TTD) in all exposure groups compared to controls.
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