vNOTES hysterectomy is a scarless minimally invasive method with a vaginal approach to the abdominal cavity combined with endoscopic overview. Studies have shown that patients who underwent vNOTES hysterectomy had less pain and shorter hospital stay than after laparoscopic hysterectomy.
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Risk Analysis of Neurological Deterioration Associated With Fluid Insufflation in Uniportal Spine Endoscopy: A Case Series and Literature Review.
Int J Spine Surg
March 2025
NeuroSpine Surgery Research Group (NSURG), Randwick, Australia.
Background: Uniportal spine endoscopy is a minimally invasive technique gaining widespread popularity, but fluid insufflation during the procedure poses risks of neurological deterioration. The present study examines these risks through a case series and literature review.
Methods: A review of the literature was conducted to identify reported complications related to fluid insufflation.
Rapidly separable bubble microneedle-patch system present superior transdermal mRNA delivery efficiency.
Int J Pharm
March 2025
Bioinformatics Center of AMMS, Beijing, People's Republic of China. Electronic address:
Traditional mRNA vaccine formulation loaded by lipid nanoparticle (mRNA-LNP) has several shortcomings in clinical application, including the need for cryopreservation, discomfort associated with intramuscular injections, and the risk of liver aggregation. Dissolvable microneedles (DMNs), as a novel transdermal drug delivery platform, can overcome the skin barrier to deliver drugs directly into the skin in a minimally invasive manner. However, mRNA-LNP is unstable and easily degraded during the solidification of DMN.
View Article and Find Full Text PDFMeasurements of Lung Size in Ultrasound and Magnetic Resonance Imaging in Congenital Diaphragmatic Hernia - A Comparison of Prenatal Imaging Techniques.
Ultraschall Med
March 2025
Department of Neonatology, University Medical Centre Mannheim, Mannheim, Germany.
To investigate the correlation between different prenatal imaging techniques in congenital diaphragmatic hernia (CDH) and their prognostic value.209 fetuses with CDH were enrolled in this retrospective cohort study. The prenatal ultrasound-based and MRI-based (MRI: magnetic resonance imaging) observed-to-expected lung-to-head ratio (o/e-LHR) and MRI-based relative fetal lung volume (rFLV) were evaluated and compared.
View Article and Find Full Text PDFHysteroscopic Criteria for the Diagnosis of Chronic Endometritis: a Systematic Review and Diagnostic Test Accuracy Meta-analysis.
Am J Obstet Gynecol
March 2025
Division of Gynecology and Obstetrics, Department of Surgical Sciences, University of Cagliari, Cagliari, Italy.
Objective: To assess the diagnostic accuracy of current hysteroscopic criteria compared with histopathological analysis (with or without additional immunohistochemistry) for the detection of chronic endometritis.
Data Sources: MEDLINE, Scopus, SciELO, Embase, ClinicalTrials.gov, Cochrane Central Register of Controlled Trials, LILACS, conference proceedings, and international controlled trials registries were searched without date limit or language restrictions.
[Robotic Gastrectomy Contributed to Safe Surgery in a Patient with Gastric Cancer with Severe Pulmonary Dysfunction Due to Myasthenia Gravis].
Gan To Kagaku Ryoho
February 2025
Dept. of Digestive Surgery, Kyoto First Red Cross Hospital.
Robotic gastrectomy is a safe and minimally invasive approach that may reduce the risk of complications in patients with severely impaired pulmonary function. Here, we report the successful treatment of an 80-year-old patient with gastric cancer and myasthenia gravis(MG)using perioperative respiratory rehabilitation and robotic gastrectomy with D2 lymphadenectomy. Patients with gastric cancer and severe pulmonary dysfunction are at a risk of postoperative respiratory disorders, including severe pneumonia.
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