A study was made of the effect of poly(ADP-ribosylation) of proteins on the formation and repair of single-strand DNA breaks in gamma-irradiated (50 Gy) permeable Zajdela ascites hepatoma cells permeabilized by the treatment with 0.05% triton X-100. Incubation of gamma-irradiated permeable cells in conditions promoting DNA synthesis and providing ADP-ribosylation (in the presence of 1 mM NAD) did not cause any substantial changes in the formation of single-strand DNA breaks and did not influence their repair.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Membranes Based on Polyvinylidene Fluoride and Radiation-Grafted Sulfonated Polystyrene and Their Performance in Proton-Exchange Membrane Fuel Cells.
Polymers (Basel)
September 2022
Kurnakov Institute of General and Inorganic Chemistry RAS, 31 Leninsky Avenue, 119991 Moscow, Russia.
Proton-exchange membranes based on gamma-irradiated films of PVDF and radiation-grafted sulfonated polystyrene with an ion-exchange capacity of 1.8 meq/g and crosslinking degrees of 0 and 3% were synthesized. A solvent-free, environmentally friendly method of styrene grafting from its aqueous emulsion, with a styrene content of only 5 vol.
View Article and Find Full Text PDFOptimized molecular imprints in gamma-irradiated collagen shields of an antifungal drug: In vitro characterization, in-vivo bioavailability enhancement.
Eur J Pharm Biopharm
September 2021
Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Ahram Canadian University, 6 October, Cairo, Egypt; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Helwan University, Ain Helwan, Cairo, Egypt.
The purpose of this manuscript is to develop sustained release molecularly imprinted voriconazole (VOR) that were loaded into collagen shield (CS) for ocular treatment of fungal keratitis. Various molecularly imprinted polymer (MIP) formulae were prepared by a precipitation polymerization technique. Different monomers and crosslinkers were tested to obtain better binding capacity.
View Article and Find Full Text PDFThe impact of gamma-irradiation from radioactive liquid wastewater on polymeric structures of nanofiltration (NF) membranes.
J Hazard Mater
February 2021
Dept. of Civil and Environmental Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea. Electronic address:
In this study, the impacts of gamma-irradiation from the low- and intermediate-level liquid radioactive wastewaters (LILW) to polyamide (PA) structures of nanofiltration (NF) membranes were investigated. As the gamma-irradiation increased to 300 kGy in the aqueous solution at 5 bar, both the salt rejection and the water permeability of NF membranes were decreased from 95.6 ± 0.
View Article and Find Full Text PDFFoliar application of gamma radiation processed chitosan triggered distinctive biological responses in sugarcane under water deficit stress conditions.
Int J Biol Macromol
October 2019
Plant Stress Physiology and Biotechnology Section, Nuclear Agriculture and Biotechnology Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400 085, India.
Chitosan, being one of the most promising biological macromolecules, has an immense scope in agriculture to boost crop growth and defense responses. In this study, chitosan was exposed to gamma rays in order to obtain a low molecular weight derivative. Viscometric characterization showed a sharp decrease in molecular weight and FTIR based analysis confirmed retention of structural integrity of the polymer upon gamma irradiation.
View Article and Find Full Text PDFMaintenance of claudin-3 expression and the barrier functions of intercellular junctions in parotid acinar cells via the inhibition of Src signaling.
Arch Oral Biol
September 2017
Department of Physiology, Nihon University School of Dentistry at Matsudo, Matsudo, Chiba 271-8587, Japan; Research Institute of Oral Science, Nihon University School of Dentistry at Matsudo, Matsudo, Chiba 271-8587, Japan. Electronic address:
Objectives: Salivary acinar and duct cells show different expression patterns of claudins, which may reflect their different functions. To study the role of claudins in saliva secretion, we examined alterations in the expression patterns of cell adhesion molecules in parotid glands of γ-irradiated rats and analyzed the influence of those changes on intercellular barrier function using primary cultures of parotid acinar cells.
Design: Rats were γ-irradiated with doses of 5, 15 or 20Gy, and expression levels of cell adhesion molecules were examined by immunoblotting analysis.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!