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| http://dx.doi.org/10.1097/AS9.0000000000000312 | DOI Listing |
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Saint Paul, the Apostle, and the Gastaut-Geschwind syndrome.
Dement Neuropsychol
December 2024
Faculdade Santa Casa Belo Horizonte, Belo Horizonte MG, Brazil.
The interface between epilepsy and religiosity has been a long-standing matter of debate. Epilepsy has affected several religious leaders throughout history. Hyperreligiosity may be observed in patients with temporal lobe epilepsy as a component of the so-called Gastaut-Geschwind syndrome which involves other behavioral and personality traits such as hyposexuality, viscosity, philosophical concerns, sense of personal destiny, hypergraphy, emotionality, and irritability.
View Article and Find Full Text PDFTiming Matters: Late, but Not Early, Exercise Training Ameliorates MASLD in Part by Modulating the Gut-Liver Axis in Mice.
J Pineal Res
December 2024
Department of Medicine, Division of Endocrinology, Leiden University Medical Center, Leiden, The Netherlands.
Metabolic dysfunction-associated steatotic liver disease (MASLD) affects two billion people worldwide and is currently mostly treatable via lifestyle interventions, such as exercise training. However, it is unclear whether the positive effects of exercise are restricted to unique circadian windows. We therefore aimed to study whether the timing of exercise training differentially modulates MASLD development.
View Article and Find Full Text PDFA pilot randomized clinical trial of a smartphone-based application to support at-home PSA screening and culturally tailored prostate cancer education for African American men: A study protocol.
Contemp Clin Trials
December 2024
TSET Health Promotion Research Center, Stephenson Cancer Center, the University of Oklahoma Health Science Centers, Oklahoma City, OK, USA; Department of Family and Preventive Medicine, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA. Electronic address:
Background: Prostate cancer is the most diagnosed cancer in Black/African American men (AA) and the second‑leading cause of cancer-related deaths. A prostate-specific antigen (PSA) blood test is an early detection screening tool for prostate cancer, but uptake of PSA screening remains low among AA men. Greater PSA screening rates among AA men, coupled with earlier treatment, may reduce disparities in prostate cancer outcomes, including mortality.
View Article and Find Full Text PDFConsidering the impact of the chirality of therapeutic nanoparticles on cancer therapy.
Nanomedicine (Lond)
October 2024
Beijing Key Laboratory of Micro-Nano Energy & Sensor, Center for High-Entropy Energy & Systems, Beijing Institute of Nanoenergy & Nanosystems, Chinese Academy of Sciences, Beijing, 101400, P. R. China.
"Inadequate understanding of chirality has potentially disastrous consequences. "Genius on the left, madman on the right" is not an exaggerated verse in the field of chiral research, but a realistic warning…".
View Article and Find Full Text PDFObjective: Along with the known effects of stress on brain structure and inflammatory processes, increasing evidence suggest a role of chronic stress in the pathogenesis of Alzheimer's disease (AD). We investigated the association of accumulated stressful life events (SLEs) with AD pathologies, neuroinflammation, and gray matter (GM) volume among cognitively unimpaired (CU) individuals at heightened risk of AD.
Methods: This cross-sectional cohort study included 1,290 CU participants (aged 48-77) from the ALFA cohort with SLE, lumbar puncture (n = 393), and/or structural magnetic resonance imaging (n = 1,234) assessments.
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