Schwannomas are benign tumors of the peripheral nervous system that arise from Schwann cells. Intracranial schwannomas most commonly arise from the vestibulocochlear nerve, followed by the fifth nerve. However, optic nerve sheath schwannomas are very rare due to the lack of Schwann cells on it. A few exceptional cases of optic nerve sheath schwannoma have been described in the literature. In this article, we report a rare case of primary optic nerve sheath schwannoma in a 48-year-old woman who presented with progressive visual loss and left-sided proptosis. Magnetic resonance imaging revealed a well-demarcated intraconal orbital mass with cystic appearance and rim enhancement. The diagnosis of optic nerve schwannoma was proposed and confirmed histologically after surgical resection.
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http://dx.doi.org/10.1016/j.radcr.2023.08.085 | DOI Listing |
Vision Res
January 2025
Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Elevated intraocular pressure (IOP) is a significant risk factor for glaucoma, causing structural and functional damage to the eye. Increased IOP compromises the metabolic and structural integrity of retinal ganglion cell (RGC) axons, leading to progressive degeneration and influencing the ocular immune response. This study investigated early cellular and molecular changes in the retina and optic nerve (ON) following ocular hypertension (OHT).
View Article and Find Full Text PDFOphthalmic Plast Reconstr Surg
January 2025
Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts.
A 73-year-old male with a history of incidentally diagnosed Paget disease of bone affecting the skull and left orbit 2 years prior presented with 3 months of vision loss, proptosis, and periorbital swelling of the OS. Examination showed best-corrected Snellen visual acuity of 20/150 in the affected eye, intact motility, 7 mm of relative proptosis, significant dilated and tortuous "corkscrew" conjunctival vessels, serous choroidal and retinal detachments, optic nerve hyperemia, and venous tortuosity and dilation. Although the bony lesions in the left orbit were stable from 1 year prior on imaging, the diagnostic angiogram demonstrated osseous blush and hypervascularity of the lesion.
View Article and Find Full Text PDFFront Pediatr
January 2025
Department of Pediatrics, The Affiliated Yangming Hospital of Ningbo University, Yuyao People's Hospital, Yuyao Branch of the Second Affiliated Hospital of Zhejiang University School of Medicine, Ningbo, China.
Introduction: Increased intracranial pressure (ICP) is common with viral encephalitis in children which is associated with complications and prognosis. The optic nerve sheath diameter (ONSD) is a new indicator for the assessment of intracranial pressure using ultrasound, CT scan and MRI imaging. Given the influence of physical development on ONSD size in children, we expect more accurate assessment of intracranial pressure with ONSD/ETD (eyeball transverse diameter) ratio by ultrasound.
View Article and Find Full Text PDFCureus
December 2024
Ophthalmology, Medical Teaching Institution (MTI) Khyber Teaching Hospital, Peshawar, PAK.
Optic neuritis (ON) is the inflammation of the optic nerve. 'Typical' ON is commonly associated with multiple sclerosis (MS) and its classic triad includes sudden loss of vision, pain with eye movement and dyschromatopsia. It usually has good visual outcome irrespective of treatment.
View Article and Find Full Text PDFHeliyon
January 2025
Department of Optometry and Vision Science, School of Rehabilitation, Tehran University of Medical Science, Tehran, Iran.
Purpose: We aimed to build a machine learning-based model to predict radiation-induced optic neuropathy in patients who had treated head and neck cancers with radiotherapy.
Materials And Methods: To measure radiation-induced optic neuropathy, the visual evoked potential values were obtained in both case and control groups and compared. Radiomics features were extracted from the area segmented which included the right and left optic nerves and chiasm.
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