The development of α-glucosidase inhibitors is essential for the prevention of type II diabetes. Previous research has investigated inhibition using isolated α-glucosidase, which may not accurately reflect physical processes. The method presented in this study aims to establish a rapid and inexpensive in vivo method to study the inhibition of α-glucosidase activity using as a model organism. This method can be used to calculate the IC value of compounds of interest for inhibition of α-glucosidase activity. The method established in this study can be used for screening of anti-diabetic compounds. •A rapid and inexpensive method to study the inhibition of α-glucosidase activity.•This method can be used to calculate the IC value of compounds of interest for inhibition of α-glucosidase activity.•This is a useful method for in vivo screening of anti-diabetic compounds.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10511798 | PMC |
| http://dx.doi.org/10.1016/j.mex.2023.102373 | DOI Listing |
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