Mechanically Enhanced Soft Contact Lenses from Photodimerization Cross-Linking.

ACS Omega

Department of Polymer Science and Engineering, Polymeric Nanomaterials Laboratory, Kyungpook National University, 1370 Sankyuk-dong, Buk-ku, Deagu 702-701, Korea.

Published: September 2023

AI Article Synopsis

  • The study created three new acrylic monomers with a cinnamate group to make soft contact lenses by mixing them with HEMA and using bulk polymerization.* -
  • UV spectral analyses confirmed that the cinnamate group in the polymer underwent a photodimerization reaction when exposed to UV light, leading to enhanced mechanical properties.* -
  • The UV-cured lenses maintained their shape in a water-swollen state and exhibited less tearability compared to conventional lenses, despite having slightly reduced water content and lower water contact angles.*

Article Abstract

In this study, we synthesized three novel acrylic monomers with a cinnamate group. We then mixed each monomer with 2-hydroxyethyl methacrylate (HEMA) to prepare soft contact lenses through bulk polymerization. Fourier transform infrared (FT-IR) and UV spectral analyses confirmed that the cinnamate group in the polymer undergoes a photodimerization reaction via UV irradiation. After UV curing, the present lenses stably maintained their shapes even in a water-swollen state and showed significantly improved mechanical properties compared to conventional lenses manufactured using a cross-linking agent. These lenses showed slightly lower water contact angles than the conventional lenses, although the water content was slightly reduced. The present photodimerization cross-linking method was found to be useful in reducing the tearability of soft lenses.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515589PMC
http://dx.doi.org/10.1021/acsomega.3c04489DOI Listing

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