Serum levels of 25 OH-D, Calcium, Phosphorus and Alkaline phosphatase were measured in 53 children. These children, immigrants for 3/4, 3 to 6 years old, were in good health, and usually followed in a medical advice of PMI in the center of the city. During the month of february, march, april, the half of immigrant children have a serum 25 OH-D deficiency and high alkaline phosphatase, when european children have a normal 25 OH-D level and low alkaline phosphatase. After a stay in their origin country, in september, october, the children come back with a normal 25 OH-D level. Difference between winter and autumn is very significative. The risk factors of a vitamin D deficiency are studied.

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