Cardiac resynchronization therapy in patients with a coronary sinus reducer: a case series.

Eur Heart J Case Rep

Department of Cardiology, Heart Center Lucerne, Luzerner Kantonsspital, Spitalstrasse 16, 6002 Luzern, Switzerland.

Published: September 2023

AI Article Synopsis

  • Reducing venous drainage from the coronary sinus using the CSR System™ can alleviate symptoms and enhance quality of life for patients with refractory angina.
  • This case series reports on three patients, confirming that cardiac resynchronization therapy (CRT) is workable for those with the CSR implant, including the successful extraction of a left ventricular lead.
  • While CRT shows promise, caution is advised when considering lead extraction due to potential complications, suggesting that alternative approaches should be explored early in treatment.

Article Abstract

Background: Reducing venous drainage of the coronary sinus is a promising intervention for refractory angina. Coronary Sinus Reducer (CSR) System™ effectively treats patients with refractory angina, possibly by increasing coronary collateral circulation, and leads to an improvement in their symptoms and quality of life. In patients with impaired left ventricular function and electrocardiographic dyssynchrony, cardiac resynchronization therapy (CRT) is an established treatment. However, there is only one published case report of CRT in a patient implanted with a CSR system. We present the first case series of CRT in patients implanted with the CSR system.

Case Summary: This case series describes three patients. The first case demonstrated that CRT is feasible in patients implanted with a CSR system. The second case is the first report of a left ventricular lead extraction after CSR, and the third case was complicated due to the patient's medical history; however, CSR system implantation was feasible without major complications.

Discussion: Our results suggest that CRT is feasible in patients implanted with a CSR system, and lead extraction after CSR system implantation is possible. However, lead extraction in cases of severe adhesions around the CSR system and the coronary sinus may be associated with a high risk of complications; alternative options should be discussed at an early stage.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516338PMC
http://dx.doi.org/10.1093/ehjcr/ytad455DOI Listing

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