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The use of peroneus brevis in lower limb reconstruction-What we have learned from 49 cases.
Injury
August 2024
Department of Plastic and Reconstructive Surgery, Southmead Hospital, North Bristol NHS Trust, Southmead Road, Bristol BS10 5NB, United Kingdom.
Introduction: There are many suitable techniques for the treatment of soft tissue defects of the lower limb. Older subjects often with multiple comorbidities, presenting with a laterally located and complex defect, can be challenging to treat. This cohort are often unsuited to long procedures or multi-stage reconstruction and so one is faced with a paucity of options.
View Article and Find Full Text PDFMacular hole surgery follow-up with spectral domain-optical coherence tomography-guided facedown posturing.
Int Ophthalmol
April 2024
Department of Ophthalmology, Baskent University, Ankara, Turkey.
Purpose: The main treatment for macular hole (MH) is pars plana vitrectomy, with or without internal limiting membrane (ILM) peeling, followed by gas tamponade and face-down positioning (FDP). This study aims to present the anatomical and visual outcomes following MH repair with optical coherence tomography (OCT)-guided FDP.
Methods: Thirty-two patients who underwent surgery for idiopathic MH were enrolled.
Modified Mustardé and Superolateral Periosteal Flaps for Full-Thickness Defects of Medial and Central Lower Eyelid: A Case Series.
Ann Plast Surg
April 2024
From the Plastic and Reconstructive Surgery, General Surgery Department, Nakornping Hospital, Chiang Mai, Thailand.
Background: Reconstructing full-thickness defects involving 50% to 75% of the horizontal length of the lower eyelid after medial and central full-thickness block resection can be challenging. As a disadvanatge, 1-stage reconstructions may require a free graft reconstruction of the posterior lamella. In addition, 2-stage reconstructions are associated with several complications, including erythema, and the eye must be temporarily closed after surgery.
View Article and Find Full Text PDFDiagnosis and laboratory monitoring of acquired hemophilia A.
Hematology Am Soc Hematol Educ Program
December 2023
The Royal London Hospital Haemophilia Centre, Bart Health NHS Trust, London, UK.
Acquired hemophilia A (AHA) is a rare disorder in which autoantibodies against factor VIII (FVIII) lead to a bleeding phenotype that varies from life-threatening to no bleeding at all. Prolonged activated partial thromboplastin times (APTT) in patients with a bleeding phenotype should be investigated to rule out AHA and should never be ignored in a preprocedure patient. Most inhibitors in AHA are heat and time dependent, so mixing studies performed only on an immediate mix are not useful: both lupus anticoagulants and treatment with direct oral anticoagulants can coexist with AHA and confound the diagnosis.
View Article and Find Full Text PDFMeasurement of Urinary Gc-Globulin by a Fluorescence ELISA Technique: Method Validation and Clinical Evaluation in Septic Patients-A Pilot Study.
Molecules
September 2023
Department of Anesthesiology and Intensive Therapy, Medical School, University of Pécs, 7624 Pécs, Hungary.
A major complication of sepsis is the development of acute kidney injury (AKI). In case of acute tubular damage, Gc-globulin, a known serum sepsis marker is increasingly filtrated into the urine therefore, urinary Gc-globulin (u-Gc) levels may predict septic AKI. We developed and validated a competitive fluorescence ELISA method for u-Gc measurement.
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