Angioedema is potentially life-threating swelling of integument and mucosa that has multiple potential aetiologies with varying mechanisms. Drug-induced angioedema is often easily correlated with the offending agent and can be prevented with discontinuation of the medication. Many medications have now been implicated in drug-induced angioedema but the two most common are ACE inhibitors and non-steroidal anti-inflammatory drugs (NSAIDs). This case highlights severe angioedema secondary to celecoxib and reviews varying aetiologies of angioedema and NSAID hypersensitivity reactions.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10533717 | PMC |
| http://dx.doi.org/10.1136/bcr-2023-255446 | DOI Listing |
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Disposition of emergency department patients presenting with angiotensin-converting enzyme inhibitor-induced angioedema.
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Division of Clinical Immunology and Allergy, Department of Chest Diseases, Faculty of Medicine, Ankara University, Ankara, Turkiye.
Article Synopsis
- The study aimed to explore the connection between serum antidrug antibodies (ADAbs), hypersensitivity reactions, and local injection site reactions in patients with ankylosing spondylitis and rheumatoid arthritis who were on anti-TNF treatments.
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December 2024
Division of Allergy and Immunology, Department of Medicine, Western University, London, ON, Canada.
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Heliyon
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Department of Radiology, Ibn Sina Specialized Hospital, Jenin, P200, Palestine.
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