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Doxycycline post-exposure prophylaxis for preventing bacterial sexually transmitted infections (STIs): Are clinical providers supportive?
Int J STD AIDS
December 2024
New York State Department of Health AIDS Institute, Albany, NY, USA.
Background: Bacterial sexually transmitted infections (STIs) continue to increase in the United States. Despite evidence of the effectiveness of doxycycline post-exposure prophylaxis (Doxy-PEP) to prevent STIs, little is known about providers' attitudes and willingness to implement Doxy-PEP.
Methods: An online questionnaire was sent to 575 clinical providers in New York State in September 2022.
Doxycycline Postexposure Prophylaxis to Prevent Bacterial Sexually Transmitted Infection.
JAMA
December 2024
Section of Infectious Diseases and Global Health, University of Chicago Medicine, Chicago, Illinois.
DOXY do, or DOXY Don't? Syphilis and doxycycline post-exposure prophylaxis: A case report.
Int J STD AIDS
December 2024
Genitourinary Clinic, Department of Dermatology and Venereology, Mater Dei Hospital, Msida, Malta.
The resurgence of syphilis across Europe has led to a growing number of atypical cases, often characterised by varied symptoms that can delay diagnosis. We report the case of a young man who has sex with men (MSM), presenting with persistent headaches and swelling of the forehead suggestive of giant cell arteritis (GCA). Despite a recent negative syphilis test, further investigations confirmed the diagnosis of neurosyphilis.
View Article and Find Full Text PDFKnowledge, uptake and intention to use antibiotic post-exposure prophylaxis and meningococcal B vaccine (4CMenB) for gonorrhoea among a large, online community sample of men and gender-diverse individuals who have sex with men in the UK.
PLOS Glob Public Health
December 2024
Blood Safety, Hepatitis, STI & HIV Division, UK Health Security Agency, London, United Kingdom.
Article Synopsis
- Novel STI prevention methods like doxycycline post-exposure prophylaxis (doxyPEP) and meningococcal B vaccination (4CMenB) are being explored to help control STIs, especially among men and gender-diverse individuals in the UK.
- A survey involving 1,106 participants found that only 34% were aware of antibiotic PEP, with just 8% having reported ever using it; however, 51% expressed an intention to use doxyPEP and 64% for 4CMenB.
- Higher rates of PEP usage and intention to use doxyPEP and 4CMenB were associated with higher sexual risk behaviors and participants who were already using other preventative measures like
Article Synopsis
- - The text emphasizes that new antiretroviral drugs and formulations are continuously being developed for HIV prevention and treatment, highlighting the importance of updated strategies to manage the virus effectively.
- - A panel of expert physician scientists has compiled updated recommendations for 2024 based on extensive literature reviews and data from scientific conferences, focusing on treatment protocols tailored to specific patient needs.
- - Current recommendations advocate for antiretroviral therapy for all individuals with HIV, primarily using integrase strand transfer inhibitors, while also offering alternatives for those with unique circumstances, and suggesting both oral and injectable options for HIV prevention.
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