Background: We aim to describe outcomes of elderly patients undergoing salvage surgery for laryngeal cancer and to characterize the interplay of age with various other factors in this growing population.
Methods: Using the National Cancer Database, we identified cases of salvage laryngectomy in patients who failed chemoradiation. An age cutoff of 70 years was used to separate subjects into two groups. Various factors were compared.
Results: Of the 825 patients included, 166 (20.1%) were elderly. Elderly patients had worse overall survival (p = 0.001), higher 30-day and 90-day mortality (p = 0.006, p < 0.001), and a longer length of stay (LOS) (p = 0.015). LOS over 1 week was associated with worse survival (p = 0.032).
Conclusion: Elderly patients had worse overall perioperative survival than their younger counterparts. LOS and 30-day readmissions were associated with higher risk of mortality in this group. We provide a contemporary set of relevant information for head and neck cancer providers to consider in this growing population.
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http://dx.doi.org/10.1002/hed.27525 | DOI Listing |
Plast Reconstr Surg Glob Open
January 2025
From the Division of Plastic Surgery, UC San Diego Health, San Diego, CA.
Background: Breast prosthesis infections are challenging and traditionally managed with prosthesis removal and delayed reconstruction. Single-application negative pressure wound therapy with instillation and dwell (NPWTi-d) has shown promise for salvaging infected implants, though prior studies have been small and heterogeneous. This study analyzes outcomes and compares protocols from four institutions.
View Article and Find Full Text PDFHead Neck
January 2025
Department of ENT-Head & Neck Surgery, Singapore General Hospital, Singapore, Singapore.
Background: Local recurrence of nasopharyngeal carcinoma (NPC) occurs in 10%-20% of patients, with salvage potential in early recurrences. Yet, clear surveillance protocols are lacking. We compare survival outcomes and suitability for salvage in symptomatic and incidentally detected locally recurrent NPC.
View Article and Find Full Text PDFJ Pak Med Assoc
January 2025
Department of Plastic Surgery, Shifa International Hospital, Islamabad, Pakistan.
Objective: To assess the functional outcomes of patients undergoing lower limb reconstruction with vascularised fibula following tumour resection in a tertiary care setting.
Methods: The single-centre, retrospective, observational study was conducted at the Shifa International Hospital, Islamabad, Pakistan, and comprised data from January 1, 2017, to December 31, 2022, of patients who underwent lower limb reconstruction with vascularised fibula following oncological resection. Functional outcome was assessed using Musculoskeletal Tumour Society score.
BMJ Open Diabetes Res Care
January 2025
Department of Surgery, Woodlands Health, Singapore
Introduction: To compare the clinical outcomes and healthcare utilization of patients enrolled in the multidisciplinary Diabetic Foot in Primary and Tertiary (DEFINITE) Care program with a matched historical cohort and estimate the program's long-term cost-effectiveness using simulation.
Research Design And Methods: This study consisted of two components: a 1-year observational outcome evaluation and a long-term simulation-based cost-effectiveness analysis (CEA). We conducted an observational study to analyze 2798 patients with diabetic foot ulcers (DFUs) enrolled in the program between June 2020 and June 2021 (DEFINITE Care group) and 5462 patients with DFUs from June 2016 to December 2017 as historical controls.
BMJ Case Rep
January 2025
Department of Orthopaedic Surgery, Pontificia Universidad Catolica de Chile, Santiago, RM, Chile
The hindfoot is an uncommon site for malignant tumours. While limb salvage procedures are now more common for treating bone sarcoma, there is limited information available on hindfoot reconstruction alternatives because of its low incidence and its challenging outcomes. We present a case report of a man in his late 60s with synovial sarcoma affecting the right heel (calcaneus and soft tissue).
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