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Sacubitril/valsartan on right ventricular-pulmonary artery coupling and albumin-bilirubin score in heart failure in Chinese patients with reduced ejection fraction.
J Cardiothorac Surg
January 2025
Department of Cardiology, Zhengzhou University People's Hospital, Henan Provincial People's Hospital, Fuwai Central China Cardiovascular Hospital, Heart Center of Henan Provincial People's Hospital, Zhengzhou, Henan, 450003, China.
Objective: Impaired right ventricular (RV)-pulmonary arterial (PA) coupling, calculated by measuring the tricuspid annular plane systolic excursion (TAPSE) to pulmonary artery systolic pressure (PASP), can be used as an early indicator of right ventricular dysfunction (RVD) in patients with heart failure with a reduced ejection fraction (HFrEF). Patients suffering from HFrEF experience improvements in left ventricular (LV) function through the administration of sacubitril/valsartan therapy. In addition, the albumin-bilirubin (ALBI) score was associated with the fluid overload status and adverse clinical outcomes in patients with heart failure.
View Article and Find Full Text PDFRight ventricular function and anemia in heart failure with preserved ejection fraction.
Front Cardiovasc Med
November 2024
Emergency Department, Wangjing Hospital of China Academy of Chinese Medical Sciences, Beijing, China.
Background: Anemia is a common complication in patients with heart failure and is associated with left ventricular systolic dysfunction. However, its role in right ventricular (RV) function has not been evaluated.
Methods: We retrospectively analyzed the electronic medical data of 1,014 Heart Failure with Preserved Ejection Fraction (HFpEF) patients to evaluate the relationship between anemia and RV dysfunction in patients with HFpEF and whether this relationship is influenced by classical risk factors such as smoking and hypertension.
Incremental Prognostic Value of Right Ventricular-Pulmonary Artery Coupling to a Clinical Risk Score in Tricuspid Regurgitation: The TRIO-RV Score.
J Am Soc Echocardiogr
November 2024
Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota. Electronic address:
Article Synopsis
- The study aimed to assess the prognostic value of right ventricle (RV) function and its coupling to pulmonary artery pressure in patients with tricuspid regurgitation (TR) to improve risk evaluation beyond an established clinical score.
- Researchers analyzed data from 417 patients with moderate TR and developed a new risk score by integrating RV function measures, finding significant correlations between these parameters and patient mortality during a median follow-up of nearly 4 years.
- Results showed that many patients initially categorized as low- or intermediate-risk were reclassified to higher risk when RV function metrics were included, indicating that incorporating these echocardiographic measures enhances mortality predictions in TR patients.
Right ventricular to pulmonary arterial coupling as a predictor of survival in patients undergoing mitral valve surgery for mitral regurgitation.
Eur J Cardiothorac Surg
November 2024
Department of Cardiology, St Thomas' Hospital, London, UK.
Objectives: Right ventricular-to-pulmonary artery coupling has been associated with outcomes in mitral regurgitation treated by transcatheter approaches. We evaluated right ventricular-to-pulmonary artery coupling as a predictor of survival and postoperative length of hospital stay (LOS) in patients with mitral regurgitation undergoing mitral valve surgery.
Methods: In this retrospective analysis (median follow-up: 5.
Untangling Right Ventricular-Pulmonary Artery Coupling and Pulmonary Hypertension Definitions in Transcatheter Edge-to-Edge Repair.
Am J Cardiol
November 2024
Memorial Healthcare System, Hollywood, Florida; Florida Atlantic University, Boca Raton, Florida. Electronic address:
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