AI Article Synopsis

  • Girls and women suffer from headaches more often than boys and men, prompting a study to explore gender differences in treatment effectiveness within the Dresden Child and Adolescent Headache Program (DreKiP).
  • A total of 140 patients participated in a structured 15-hour program, and data were collected on headache frequency, intensity, and related daily limitations over six and twelve months post-treatment.
  • Results indicated that girls had significantly higher headache frequencies and limitations in daily life compared to boys, but both genders showed improvement over time; however, there was no difference in treatment response between genders, suggesting that the factors influencing headaches in girls should be further explored.

Article Abstract

Background: Girls and women are more frequently affected by headache than boys and men. The influence of gender on the effectiveness of headache therapies has so far been hardly investigated. We examined gender differences in the outpatient multimodal Dresden Child and Adolescent Headache Program DreKiP.

Methods: We treated 140 patients with primary headache in a 15-hour structured group program. At baseline (T0) and six (T1) and twelve months (T2) after the end of the program, data on headache-related limitation of daily activities (PedMIDAS) as well as headache frequency, intensity, and pain-related disability (P-PDI) were collected. Retrospectively, these data were analyzed separately for girls and boys.

Results: For 91 patients (9-19 years, median = 15; 71.4 % female) data were available for at least two measurement time points. Girls showed significantly higher headache frequency than boys at all time points (median headache days/last three months at T0: ♀ 43, ♂ 20; T1: ♀ 32, ♂ 12; T2: ♀ 28, ♂ 9) as well as numerically higher headache-related limitation of daily life. There were significant effects over time with a decrease in headache frequency (F (2.88) = 5.862; p = 0.004) and improvement in daily functioning (F (2.92) = 5.340; p = 0.006). There was no gender-specific treatment response.

Discussion: The DreKiP therapy shows effects in girls and boys with primary headache. Higher headache frequencies and everyday life restrictions in girls may have hormonal but also psychosocial causes and should be addressed in educational measures.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10959813PMC
http://dx.doi.org/10.1007/s00482-023-00756-zDOI Listing

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