Urachal adenocarcinoma (UA) represents a rare subset of bladder tumors involving a urachal remnant. Incidental gross hematuria is often the only presenting symptom, with patients often presenting late in their course, thereby imparting an overall poor prognosis. Although there are prior case reports, there is little literature reported and no standardized treatment guidelines. We report a case of a middle-aged male who presented with incidental gross hematuria after a fall. Workup indicated the presence of a calcified bladder dome mass and pathology reported a primary urachal adenocarcinoma with pelvic nodal involvement. Patient underwent surgical resection and subsequent adjuvant, systemic chemotherapy regimen with leucovorin, fluorouracil, and oxaliplatin (FOLFOX). We hope to bring greater awareness to this rare cause of bladder malignancy.
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http://dx.doi.org/10.7759/cureus.43849 | DOI Listing |
Int J Surg Case Rep
December 2024
Faculty of Medicine, Polytechnic University of Palestine, Hebron, Palestine; Department of Urology, Governmental Hebron Hospital, Palestine.
Introduction And Importance: Urachal carcinoma (UrC) is a rare bladder malignancy originating from the urachus. Comprising around 90 % adenocarcinomas, most cases are invasive. Urachal adenocarcinoma is less common than its non-urachal counterpart and is recognized for its aggressive nature, often diagnosed at advanced stages with a poor prognosis.
View Article and Find Full Text PDFThorac Cancer
December 2024
Department of Thoracic Surgery, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China.
Front Oncol
September 2024
Department of Gynecology and Obstetrics, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Cureus
September 2024
Radiology, Medical Center Hospital, Odessa, USA.
Urachal adenocarcinoma is a rare and aggressive bladder cancer involving the urachus, an embryological fibrous remnant of the allantois extending from the bladder to the umbilicus. Usually discovered in the advanced stages, this cancer can commonly present with a poor prognosis. We report a case of a 34-year-old male patient with an unremarkable medical history who presented to the emergency department with severe, sudden onset, sharp abdominal pain.
View Article and Find Full Text PDFAnn Med Surg (Lond)
October 2024
Cancer Research Center, Tishreen University Hospital.
Introduction: Urachal carcinomas are uncommon malignant neoplasms comprising only 0.01% of all adult cancers. Most patients were aged from 58 to 64 years at diagnosis with 60 years being the median.
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