AI Article Synopsis
- - Major thrombotic complications in myeloproliferative neoplasms (MPNs) are serious issues that can lead to high sickness rates and even death, complicating treatment.
- - The occurrence of thrombosis indicates the need for thorough risk assessment and may require adjusting treatment plans, including the use of medications to prevent further clotting issues.
- - Thrombosis is more common when MPNs are first diagnosed, especially in arteries, and once a thrombosis happens, there's a significant chance (20-33%) that it can happen again in the same area.
Article Abstract
Major thrombotic complications in myeloproliferative neoplasms (MPNs) represent an important clinical problem due to their high morbidity, the complexity of their management, and their associated mortality. The appearance of a thrombosis implies a high thrombotic risk stratification of the MPN and determines the initiation or optimization of cytoreductive treatment and the use of antiplatelet or anticoagulant therapy as secondary prophylaxis. The incidence of thrombosis at the time of diagnosis is higher than during the course of the disease, being located in the arterial territory in 60-70% of cases. Once thrombosis has occurred, up to 20-33% of patients experience thrombotic recurrence in the same initial vascular territory.
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| http://dx.doi.org/10.24875/GMM.M22000806 | DOI Listing |
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