Paleosols are frequently used to recreate past climates. In the forest-steppe zone of the Russian Plain (Lipetsk region, Russia), Early Iron and Middle Ages defensive ramparts' buried soils were discovered. The parent material and similar topographic situations served as the foundation for the comparison of buried and surface soils. Following the dynamics of the landscape from 2500 years ago to the present is possible according to detailed chrono-sequences of soils positioned in similar relief positions and in the same parent material. In this article, an analysis of 8 soils buried at various times is described. The data add to the original research and include detailed morphological descriptions that conform to international standards. Physico-chemical analysis includes determination of pH, organic and carbonate carbon, exchange cations, macro- and microelements. Numerous analytical techniques can be used to investigate issues including the genesis and deterioration of the mollic horizon, the influence of human activity on the production and preservation of Chernozems, and the degree and rate of changes in soil features driven on by climatic changes.
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http://dx.doi.org/10.1016/j.dib.2023.109536 | DOI Listing |
Environ Monit Assess
December 2024
Central Department of Geology, Tribhuvan University, Kirtipur, Kathmandu, 44600, Nepal.
Freshwater ecosystems, including high-altitude lakes, can be affected by trace metal pollution derived from a mix of natural sources and anthropogenic activities. These pollutants often collect in surface sediments, with notable concentrations in the deeper areas of lakes. To evaluate the environmental risk associated with metal contaminated sediment in Rara Lake, southern Himalaya, surface sediment samples were systematically collected in November 2018, with a subsequent specific emphasis on determinations of trace element concentrations.
View Article and Find Full Text PDFSmall
December 2024
Cardiovascular Research Center, Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02129, USA.
Autophagy is a key biological process that has proven extremely difficult to detect noninvasively. To address this, an autophagy detecting nanoparticle (ADN) was recently developed, consisting of an iron oxide nanoparticle decorated with cathepsin-cleavable arginine-rich peptides bound to the near-infrared fluorochrome Cy5.5.
View Article and Find Full Text PDFTransplant Cell Ther
December 2024
Hematology/Oncology, The Hospital for Sick Children and the University of Toronto, Toronto, Ontario, Canada.
Background: Allogeneic transplant for patients with transfusion-dependent thalassemia is challenging once there has been iron overload and chronic transfusion support.
Objective(s): A transplant strategy that reduced intensity of the preparative regimen and tailored immunosuppression to both support donor engraftment and prevent GVHD was developed for this population. The combination of a pretransplant immunosuppression phase with reduced dosing of fludarabine/prednisone, treosulfan-based preparative regimen with reduced cyclophosphamide dosing, and introduction of a calcineurin/methotrexate-free GVHD prophylaxis/engraftment supporting regimen with abatacept/sirolimus/ATG was tested.
Front Med (Lausanne)
December 2024
One Health Research Group, Univerisdad de las Americas, Quito, Ecuador.
Background: Iron overload disorders, including hereditary hemochromatosis (HH), are characterized by excessive iron accumulation, which can cause severe organ damage. HH is most associated with the C282Y mutation in Caucasian populations, but its prevalence and genetic profiles in Latin American populations remain underexplored.
Objectives: To describe the clinical manifestations, genetic profiles, and biochemical characteristics of patients with suspected iron overload disorders in a specialized hematology center in Cali, Colombia.
Life Sci
December 2024
Department of Anesthesiology, Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University & Fujian Emergency Medical Center, Fujian Provincial Key Laboratory of Emergency Medicine, Fujian Provincial Key Laboratory of Critical Medicine, Fujian Provincial Co-constructed Laboratory of "Belt and Road", Fuzhou, Fujian 350001, China. Electronic address:
Aims: Nicotine-exacerbated atherosclerosis significantly increases global mortality. Endothelial cells, which line the interior of blood vessels, are crucial for maintaining vascular function. How nicotine is involved in vascular remodeling in atherosclerosis via modulating endothelial dysfunction remains unknown.
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