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| http://dx.doi.org/10.1016/j.jdcr.2023.08.008 | DOI Listing |
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Cyclosporine-induced thrombotic microangiopathy in pregnant women: A case report and literature review.
SAGE Open Med Case Rep
January 2025
Center for Reproductive Medicine, Department of Obstetrics, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China.
Article Synopsis
- Cyclosporine A (CsA) is a popular immunosuppressant, but its connection to thrombotic microangiopathy (TMA) is uncommon and not often reported.
- A case study highlights a 34-year-old pregnant woman who developed TMA symptoms while taking CsA, but her condition improved after stopping the medication.
- This study is the first to document CsA-induced TMA in pregnancy, and it reviews previous cases to outline mechanisms, characteristics, risk factors, and detection methods for this rare side effect.
Kaempferol attenuates cyclosporine-induced renal tubular injury via inhibiting the ROS-ASK1-MAPK pathway.
Naunyn Schmiedebergs Arch Pharmacol
September 2024
The Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huaian, Jiangsu Province, China.
Cyclosporine (CSA) is a widely used immunosuppressive medication. CSA nephrotoxicity severely limits its application. Kaempferol (KPF), a naturally occurring phenolic compound, has a promising protective effect in reducing CSA-induced renal tubular injury, but the mechanism remains unknown.
View Article and Find Full Text PDFIntegrative analysis of renal microRNA and mRNA to identify hub genes and pivotal pathways associated with cyclosporine-induced acute kidney injury in mice.
Hum Exp Toxicol
November 2023
Department of Pharmacy, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Cyclosporine (CsA) is an immunosuppressive agent that often causes acute kidney injury (AKI) in children. The specific mechanisms underlying CsA-induced AKI are currently unknown. This study used an integrated network analysis of microRNA (miRNA) and mRNA expression profiles, biochemical and pathological analyses to further investigate these potential mechanisms of CsA-induced AKI.
View Article and Find Full Text PDFDevelopment of cyclosporine-induced linear IgA bullous dermatosis despite concurrent use of dapsone.
JAAD Case Rep
October 2023
Department of Dermatology, Ohio State University Wexner Medical Center, Columbus, Ohio.
Cyclosporine-induced erythromelalgia.
Pract Neurol
August 2023
Department of Neurology, Hospital Británico de Buenos Aires, Buenos Aires, Argentina.
Erythromelalgia is a rare syndrome characterised by recurrent erythema, heat and burning pain in the extremities. There are two types: primary (genetic) and secondary (toxic, drug-related or associated with other diseases). We report a 42-year-old woman who developed erythromelalgia after taking cyclosporine for myasthenia gravis.
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