Pulmonary nodules are commonly encountered in medical practice, necessitating thorough evaluation due to their diverse etiologies. Identifying the underlying cause is of utmost importance, particularly in patients with a history of extrapulmonary cancer, to differentiate between metastasis and other etiologies. We present a rare case of a 24-year-old male with supraglottic squamous cancer who developed multiple pulmonary nodules, which surprisingly were caused by a rare infectious agent. The patient presented with bilateral infiltrates on imaging, raising strong suspicion of metastatic disease from primary cancer. However, bronchoscopy and biopsy revealed no malignancy but confirmed the presence of , leading to a change in the treatment approach from palliative to curative. This case highlights the importance of considering other etiologies, especially infections, in patients with cancer and pulmonary nodules. Accurate diagnosis is crucial to guide appropriate management decisions and optimize patient outcomes.
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http://dx.doi.org/10.7759/cureus.43796 | DOI Listing |
World J Surg Oncol
January 2025
Department of General Thoracic Surgery, Friendship Hospital, No. 2 Yinghua East Road, Chaoyang District, 100029, Beijing, China.
Background: The aim of this study was to compare the surgical efficacy of one-stage and two-stage video-assisted thoracoscopic surgery (VATS) for bilateral multiple pulmonary nodules (BMPNs).
Methods: A retrospective analysis was made of 156 patients, 84 who underwent one-stage and 72 who underwent two-stage VATS for BMPNs at our department between January 2019 and December 2022. Perioperative and long-term outcomes were compared between the two groups using propensity score-matched (PSM) analysis.
BMC Cancer
January 2025
Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, 450052, China.
Background: An increase in the prevalence of lung cancer that is not smoking-related has been noticed in recent years. Unfortunately, these patients are not included in low dose computer tomography (LDCT) screening programs and are not actually considered in early diagnosis. Therefore, improved early diagnosis methods are urgently needed for non-smokers.
View Article and Find Full Text PDFBMC Cancer
January 2025
Department of Pulmonary and Critical Care Medicine, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Background: Primary pulmonary Mucosa-associated lymphoid tissue (MALT) lymphoma is a sporadic disease with a favorable prognosis. Particularly, pulmonary MALT lymphoma coexisting with lung cancer is not only rare but also prone to misdiagnosis. The clinical characteristics and prognostic factors of this co-occurrence, however, remain poorly understood.
View Article and Find Full Text PDFCurr Probl Diagn Radiol
December 2024
Chief Physician, No.215 Heping West Road, Second Hospital of Hebei Medical University, Xinhua District, Hebei Province China. Electronic address:
Background: Distinguishing between benign and malignant pulmonary nodules based on CT imaging features such as the spiculation sign and/or lobulation sign remains challenging and these nodules are often misinterpreted as malignant tumors. this retrospective study aimed to develop a prediction model to estimate the likelihood of benign and malignant lung nodules exhibiting spiculation and/or lobulation signs.
Methods: A total of 500 patients with pulmonary nodules from June 2022 to August 2024 were retrospectively analyzed.
Clin Radiol
December 2024
The Second People's Hospital Affiliated to Fujian University of Chinese Medicine, Fuzhou, China; Fujian Clinical Medical Research Center for Integrated Chinese and Western Medicine Diagnosis and Treatment of Early Stage Lung Cancer, Fuzhou, China. Electronic address:
Aim: This study aims to quantify the performance of the Brock model through a systematic review and meta-analysis and to clarify its overall accuracy in predicting malignant pulmonary nodules.
Materials And Methods: A systematic search was conducted in databases including the Cochrane Library, Excerpta Medica database (EMBASE), MEDLINE, Web of Science, Chinese Biological Medicine Database (CBM), China National Knowledge Infrastructure (CNKI), VIP, and Wanfang from their inception until May 1, 2024, to collect observational cohort studies involving the Brock model. The primary outcome was the pooled area under the receiver operating characteristic curve (ROC) the area under curve (AUC) for the Brock model.
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