AI Article Synopsis
- Reducing standard modifiable cardiovascular risk factors (SMuRFs) is essential for addressing coronary artery disease (CAD), but some patients develop CAD without any SMuRFs.
- Patients without SMuRFs who have a heart attack tend to have higher early mortality rates compared to those with at least one SMuRF.
- An international team has created a clinical pathway for managing SMuRFless CAD patients, focusing on confirming their condition, ensuring proper secondary prevention, and identifying other risk factors to improve their healthcare outcomes.
Article Abstract
Reducing the incidence and prevalence of standard modifiable cardiovascular risk factors (SMuRFs) is critical to tackling the global burden of coronary artery disease (CAD). However, a substantial number of individuals develop coronary atherosclerosis despite no SMuRFs. SMuRFless patients presenting with myocardial infarction have been observed to have an unexpected higher early mortality compared to their counterparts with at least 1 SMuRF. Evidence for optimal management of these patients is lacking. We assembled an international, multidisciplinary team to develop an evidence-based clinical pathway for SMuRFless CAD patients. A modified Delphi method was applied. The resulting pathway confirms underlying atherosclerosis and true SMuRFless status, ensures evidence-based secondary prevention, and considers additional tests and interventions for less typical contributors. This dedicated pathway for a previously overlooked CAD population, with an accompanying registry, aims to improve outcomes through enhanced adherence to evidence-based secondary prevention and additional diagnosis of modifiable risk factors observed.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10522922 | PMC |
| http://dx.doi.org/10.1016/j.jacc.2023.06.045 | DOI Listing |
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