Objectives: To assess the efficacy of repetitive transcranial magnetic stimulation (rTMS) with an H1 coil as a treatment for hopelessness in patients with major depressive disorder (MDD).
Methods: We conducted a randomised controlled trial in a tertiary psychiatric institution in Croatia, including patients diagnosed with MDD without psychotic symptoms and with clinically relevant hopelessness. High-frequency (18 Hz) rTMS with an H1 coil was administered over four weeks on the left dorsolateral prefrontal cortex. We examined changes in the Beck Hopelessness Scale (BHS) scores.
Results: We randomly assigned 51 participants to the intervention group (rTMS plus standard therapy) and 52 to the control group (standard therapy). The mean () ages were 50 (12.3) and 50 (10.4) years, and 47% and 52% of the participants were females in the intervention and control groups, respectively. Following treatment, the BHS scores decreased (unadjusted bivariate analysis, = 0.043; false discovery rate (FDR) >5%). Multivariate analysis revealed that the BHS score was reduced by 10.8% (95% confidence interval (CI: -17.8% to -3.9%) in the rTMS group and 0.7% (95% CI: 7.5% -6.1%) in the control group ( = 0.037; FDR < 5%).
Conclusions: rTMS with an H1 coil improved the symptoms of hopelessness in patients with MDD.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/15622975.2023.2251055 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A mixed-method study on physicians' perceptions of pay for performance: impact on professionalism, morality and work-life balance.
BMC Health Serv Res
January 2025
Department of Biostatistics, Ankara University, Faculty of Medicine, Morfoloji Binasi, Biyoistatistik AD, 06230, Ankara, Altindag, Turkey.
Background: Pay-for-performance system (P4P) has been in operation in the Turkish healthcare sector since 2004. While the government defended that it encouraged healthcare professionals' job motivation, and improved patient satisfaction by increasing efficiency and service quality, healthcare professionals have emphasized the system's negative effects on working conditions, physicians' trustworthiness, and cost-quality outcomes. In this study, we investigated physicians' accounts of current working conditions, their status as a moral agent, and their professional attitudes in the context of P4P's perceived effects on their professional, social, private, and future lives.
View Article and Find Full Text PDFIn this case report, we show a strategic approach to prolonging the lifespan of pathologically migrated maxillary canines with a hopeless prognosis in a 57-year-old female patient, highlighting the potential of orthodontic management for middle-aged patients to enhance both occlusion and facial esthetics while minimizing the need for extensive prosthetic treatment. According to the visual treatment objective, the nonextraction treatment plan showed advantages in the type of orthodontic tooth movement and final occlusal relationship. Therefore, considering the favorable periodontal treatment results and single-root teeth, the hopelessly migrated maxillary canines were relocated, eliminating the existing trauma from occlusion.
View Article and Find Full Text PDFSpiritual Well-Being and Hopelessness Levels in Individuals Who Have Experienced Myocardial Infarction in Turkey.
J Relig Health
January 2025
Department of Fundamental of Nursing, Ataturk University, 25000, Erzurum, Turkey.
This study aimed to investigate the relationship between spiritual well-being and hopelessness levels in individuals who have experienced myocardial infarction. The study, which was descriptive and exploratory, was conducted on patients who had experienced myocardial infarction and undergone angiography in the coronary intensive care unit and cardiology ward of Ağrı Education and Research Hospital. The population of the study consisted of 151 patients who had experienced myocardial infarction and undergone angiography between December 2022 and February 2023.
View Article and Find Full Text PDFHistological and histomorphometric evaluation of natural bovine bone substitute with hyaluronate in socket preservation-a report of three cases.
J Mater Sci Mater Med
January 2025
Department of Anatomy, Histology, Embriology, Pathology Anatomy and Pathology Histology, Faculty of Dental Medicine and Health Osijek, J.J. Strossmayer University of Osijek, Osijek, Croatia.
Tooth extraction is physiologically followed by resorption of alveolar bone. Surgical method which aims to minimise this reduction in alveolar bone with a goal to provide enough bone volume for dental implant insertion is called socket preservation. The purpose of this article was to asses clinical, histomorphometric and histological results of socket preservation conducted with natural bovine bone substitute with hyaluronate.
View Article and Find Full Text PDF"We Need Gentleness": Isolation, Loneliness, and Implications for Psychosocial Counseling Among People with HIV who are on Methadone Maintenance Treatment and Experience Common Mental Disorders in Vietnam.
AIDS Behav
January 2025
Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, USA.
The psychological experiences and needs of people with human immunodeficiency virus (HIV) who use methadone maintenance treatment and have common mental disorders in Hanoi, Vietnam remain unknown. Due to limited services for common mental disorders, optimal delivery methods for psychotherapy are also unknown. Accordingly, this qualitive study explored both symptoms of common mental disorders among this population and the preferred qualifications and characteristics of a mental health counselor.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!