The minimum expected energy cost model, which has been proposed as one of the optimization principles for movement planning, can reproduce many characteristics of the human upper-arm reaching movement when signal-dependent noise and the co-contraction of the antagonist's muscles are considered. Regarding the optimization principles, discussion has been mainly based on feedforward control; however, there is debate as to whether the central nervous system uses a feedforward or feedback control process. Previous studies have shown that feedback control based on the modified linear-quadratic gaussian (LQG) control, including multiplicative noise, can reproduce many characteristics of the reaching movement. Although the cost of the LQG control consists of state and energy costs, the relationship between the energy cost and the characteristics of the reaching movement in the LQG control has not been studied. In this work, I investigated how the optimal movement based on the LQG control varied with the proportion of energy cost, assuming that the central nervous system used feedback control. When the cost contained specific proportions of energy cost, the optimal movement reproduced the characteristics of the reaching movement. This result shows that energy cost is essential in both feedforward and feedback control for reproducing the characteristics of the upper-arm reaching movement.
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http://dx.doi.org/10.1162/neco_a_01614 | DOI Listing |
Curr Obes Rep
January 2025
Metabolism and Body Composition, Pennington Biomedical Research Center, Baton Rouge, LA, 70808, USA.
Background: Recent technological advances have introduced novel methods for measuring body composition, each with unique benefits and limitations. The choice of method often depends on the trade-offs between accuracy, cost, participant burden, and the ability to measure specific body composition compartments.
Objective: To review the considerations of cost, accuracy, portability, and participant burden in reference and emerging body composition assessment methods, and to evaluate their clinical applicability.
J Comput Chem
January 2025
Departament de Farmàcia i Tecnologia Farmacèutica, i Fisicoquímica, Facultat de Farmàcia i Ciències de l'Alimentació, Universitat de Barcelona (UB), Barcelona, Spain.
Continuum solvation models such as the polarizable continuum model and the conductor-like screening model are widely used in quantum chemistry, but their application to large biosystems is hampered by their computational cost. Here, we report the parametrization of the Miertus-Scrocco-Tomasi (MST) model for the prediction of hydration free energies of neutral and ionic molecules based on the domain decomposition formulation of COSMO (ddCOSMO), which allows a drastic reduction of the computational cost by several orders of magnitude. We also introduce several novelties in MST, like a new definition of atom types based on hybridization and an automatic setup of the cavity for charged regions.
View Article and Find Full Text PDFJ Comput Chem
January 2025
Scuola Superiore Meridionale, Napoli, Italy.
Light-driven molecular rotary motors are nanometric machines able to convert light into unidirectional motions. Several types of molecular motors have been developed to better respond to light stimuli, opening new avenues for developing smart materials ranging from nanomedicine to robotics. They have great importance in the scientific research across various disciplines, but a detailed comprehension of the underlying ultrafast photophysics immediately after photo-excitation, that is, Franck-Condon region characterization, is not fully achieved yet.
View Article and Find Full Text PDFSmall
January 2025
Institute for Ecological Research and Pollution Control of Plateau Lakes, School of Ecology and Environmental Science, Yunnan University, Kunming, Yunnan, 650504, China.
The design and fabrication of nanocatalysts with high accessibility and sintering resistance remain significant challenges in heterogeneous electrocatalysis. Herein, a novel catalyst is introduced that combines electronic pumping with alloy crystal facet engineering. At the nanoscale, the electronic pump leverages the chemical potential difference to drive electron migration from one region to another, separating and transferring electron-hole pairs.
View Article and Find Full Text PDFSensors (Basel)
January 2025
Institute of Intelligent Manufacturing Technology, Shenzhen Polytechnic University, Shenzhen 518000, China.
This paper introduces a novel energy-efficient lightweight, void hole avoidance, localization, and trust-based scheme, termed as Energy-Efficient and Trust-based Autonomous Underwater Vehicle (EETAUV) protocol designed for 6G-enabled underwater acoustic sensor networks (UASNs). The proposed scheme addresses key challenges in UASNs, such as energy consumption, network stability, and data security. It integrates a trust management framework that enhances communication security through node identification and verification mechanisms utilizing normal and phantom nodes.
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