Stem cell-like memory T (T) cell is a memory T cell subset with characteristics of long life span, consistent self-renewing, and the multipotent capacity to reconstitute the memory and effector T cell subsets. T cell is the least differentiated cell in the memory T lymphocyte system, endowed with the stem cell-like ability, and it is essential for maintaining functional immunity. In addition, owing to its robust potential for immune reconstitution, it is central player in many physiological and pathological human processes. T cell plays an important role in the occurrence and development of various autoimmune diseases. The specific role of T cell in autoimmune diseases may make it a potential target for the treatment of multiple autoimmune diseases, driving effective immune reconstitution in therapy.
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| http://dx.doi.org/10.11817/j.issn.1672-7347.2023.230051 | DOI Listing |
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