AI Article Synopsis

  • The Himalayan marmot serves as a reservoir for brucellosis, but the specific changes in their blood biochemistry when infected with Brucella are not well-understood.
  • The study aimed to investigate hematologic and biochemical changes in 24 Brucella-infected marmots compared to 24 non-infected ones through blood sample analysis.
  • Findings revealed significant increases in immune-related blood cell counts and a decrease in carbon dioxide combining power, suggesting an immune response to Brucella infection; further research is needed to fully understand these effects.

Article Abstract

Background: The Himalayan marmot (Marmota himalayana) plays a reservoir role in the epidemiology of brucellosis. However, the changes in blood biochemical parameters are still unclear in Brucella-seropositive marmots.

Objectives: The present study was designed to explore the hematologic and biochemical variable changes in Brucella-seropositive marmots.

Methods: Blood samples were collected from the dorsalis pedis vein of Himalayan marmots (24 Brucella-seropositive marmots and 24 Brucella-free marmots). Ten hematologic and 10 serum biochemical variable examinations were performed and analyzed.

Results: Our results showed that leukocyte, platelet, neutrophil, and lymphocyte counts significantly increased, while the level of carbon dioxide combining power decreased in Brucella-infected marmots. These findings indicate that Brucella triggers an immune response in Himalayan marmots.

Conclusions: This study provides a preliminary investigation of the changes in blood biochemical analytes in Brucella-infected marmots. The interaction between Brucella infection and blood biochemical indices in Himalayan marmots should be further explored.

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Source
http://dx.doi.org/10.1111/vcp.13297DOI Listing

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