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Exploring Novel Antibiotics by Targeting the GroEL/GroES Chaperonin System.
ACS Pharmacol Transl Sci
January 2025
State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao 999078, China.
Infectious diseases have affected 13.7 million patients, placing a heavy burden on society. Furthermore, inappropriate and unrequited utilization of antibiotics has led to antimicrobial resistance worldwide.
View Article and Find Full Text PDFSoil contamination by heavy metals (HM) is a critical area of research. Traditional methods involving sample collection and lab analysis are effective but costly and time-consuming. This study explores whether geostatistical analysis with GIS and open data can provide a faster, more precise, and cost-effective alternative for HM contamination assessment without extensive sampling.
View Article and Find Full Text PDFLinear Modelling of the V̇O2/PO-Relationship during Constant Work Rate Exercise.
Med Sci Sports Exerc
January 2025
Department of Movement and Sports Sciences, Ghent University, Ghent, BELGIUM.
Introduction: The linear and continuous increase in power output (PO) during ramp incremental (RI) exercise causes a distinct V̇O2/PO relationship compared to constant work rate (CWR) exercise. Current methods enabling a translation of ramp-derived PO to CWR PO assume a linear development of the CWR V̇O2/PO relationship in the heavy-intensity domain. This study aimed to model the RI versus CWR V̇O2/PO relationship to investigate whether the loss of mechanical efficiency above GET develops linearly.
View Article and Find Full Text PDFDietary purslane (Portulaca oleracea L.) leaf powder maintains growth and intestinal health in Oreochromis niloticus under chronic water-borne cadmium exposure by strengthening the gut barriers, modulating the intestinal nutrient transporters, and relieving oxidative stress.
Fish Physiol Biochem
January 2025
Department of Biological Sciences, College of Science, University of Jeddah, P.O. Box 80327, Jeddah 21589, Saudi Arabia.
High cadmium (Cd) concentrations pose a threat to aquatic life globally. This study examined the efficiency of adding purslane (Portulaca oleracea L.) leaf powder (PLP) to Oreochromis niloticus diets on Cd's negative effects.
View Article and Find Full Text PDFTheoretical Understanding of Photoluminescence and Singlet Oxygen Quantum Yields in a Few Halogenated Fluorescein Dyes.
Chem Asian J
December 2024
Department of Chemistry, Indian Institute of Technology Tirupati, Tirupati, A.P 517619, India.
Visible-light absorbing metal-free organic dyes are of increasing demand for various optoelectronic applications because of their great structure-function tunability through chemical means. Several dyes also show huge potential in triplet photosensitization, generating reactive singlet oxygen. Understanding the structure-property relationships of many well-known fluorescein dyes is of paramount importance in designing next-generation energy efficient dyes, which is currently limited.
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