Utility of fusion imaging for the evaluation of ultrasound quality in hepatocellular carcinoma surveillance.

Ultrasonography

Department of Internal Medicine and Institute of Gastroenterology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

Published: October 2023

AI Article Synopsis

  • - This study assessed the effectiveness of fusion imaging compared to conventional ultrasound (US) for monitoring hepatocellular carcinoma (HCC), using a cohort of patients who underwent both imaging techniques within the last year.
  • - Results showed significant differences in ultrasound visualization scores between the two methods; conventional US had 54.3% rated as B and 16.2% as C, while fusion imaging scored 51.4% as B and 30.5% as C, indicating better performance with fusion imaging.
  • - The analysis identified male sex as a factor linked to lower visualization scores, with the main reason for missed lesions being a limited sonic window, suggesting that fusion imaging provides a more accurate assessment in HCC surveillance.

Article Abstract

Purpose: This study evaluated the quality of surveillance ultrasound (US) for hepatocellular carcinoma (HCC) utilizing fusion imaging.

Methods: This research involved a secondary analysis of a prospectively recruited cohort. Under institutional review board approval, participants referred for surveillance US who had undergone liver computed tomography (CT) or magnetic resonance imaging (MRI) within the past year were screened between August 2022 and January 2023. After patient consent was obtained, the US visualization score in the Liver Imaging Reporting and Data System was assessed with fusion imaging at the time of examination. This score was compared to that of conventional US using the extended McNemar test. Multivariable logistic regression analysis was used to identify factors independently associated with a US visualization score of B or C. Factors limiting visualization of focal lesions were recorded during fusion imaging.

Results: Among the 105 participants (mean age, 59±11 years; 66 men), US visualization scores of B and C were assigned to 57 (54.3%) and 17 (16.2%) participants, respectively, by conventional US and 54 (51.4%) and 32 (30.5%) participants, respectively, by fusion imaging. The score distribution differed significantly between methods (P=0.010). Male sex was independently associated with US visualization scores of B or C (adjusted odds ratio, 3.73 [95% confidence interval, 1.30 to 10.76]; P=0.015). The most common reason (64.5%) for lesion nondetection was a limited sonic window.

Conclusion: Conventional US may underestimate the limitations of the sonic window relative to real-time fusion imaging with pre-acquired CT or MRI in the surveillance of HCC.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10555691PMC
http://dx.doi.org/10.14366/usg.23106DOI Listing

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