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Diversity-Related, Student-Led National Medical Organizations: Leadership Opportunities for Learners.
MedEdPORTAL
December 2024
Dean, Universidad Central Del Caribe, School of Medicine; Executive Director, Latino Medical Student Association.
Introduction: In light of the lack of diversity in academic medicine leadership, diversity-related, student-led national medical organizations (NMOs) provide a space for solace and reprieve among common peers while providing an opportunity to develop leadership competencies in a supportive environment. Despite the impact NMOs have had on cultivating generations of leaders in medicine, trainees may not identify opportunities for leadership development that are transferable to future careers in academic medicine.
Methods: We designed and implemented a dynamic 60-minute workshop with an interactive PowerPoint presentation, author-owned video testimonials (from past student leaders of NMOs), two case presentations, and reflection exercises.
Critical review of aging clocks and factors that may influence the pace of aging.
Front Aging
December 2024
Integrative Research Institute, Sacramento, CA, United States.
Background And Objectives: Aging clocks are computational models designed to measure biological age and aging rate based on age-related markers including epigenetic, proteomic, and immunomic changes, gut and skin microbiota, among others. In this narrative review, we aim to discuss the currently available aging clocks, ranging from epigenetic aging clocks to visual skin aging clocks.
Methods: We performed a literature search on PubMed/MEDLINE databases with keywords including: "aging clock," "aging," "biological age," "chronological age," "epigenetic," "proteomic," "microbiome," "telomere," "metabolic," "inflammation," "glycomic," "lifestyle," "nutrition," "diet," "exercise," "psychosocial," and "technology.
Gut-brain axis and brain health: modulating neuroinflammation, cognitive decline, and neurodegeneration.
3 Biotech
January 2025
Manipal Centre for Biotherapeutics Research, Manipal Academy of Higher Education, Karnataka Manipal, 576 104 India.
The microbiota-gut-brain axis is a pivotal medium of crosstalk between the central nervous system (CNS) and the gastrointestinal tract. It is an intricate network of synergistic molecular pathways that exert their effects far beyond their local vicinity and even affect the systemic functioning of the body. The current review explores the involvement of the gut-brain axis (GBA) in the functioning of the nervous system, with a special emphasis on the neurodegeneration, cognitive decline, and neuroinflammation that occur in Alzheimer's disease (AD) and Parkinson's disease (PD).
View Article and Find Full Text PDFMuscle Biopsy Sample Preparation and Proteomics Analysis Based on UHPLC-MS/MS.
Bio Protoc
December 2024
Key Laboratory of Sports and Physical Fitness of the Ministry of Education, Beijing Sport University, Beijing, China.
Proteomics analysis is crucial for understanding the molecular mechanisms underlying muscle adaptations to different types of exercise, such as concentric and eccentric training. Traditional methods like two-dimensional gel electrophoresis and standard mass spectrometry have been used to analyze muscle protein content and modifications. This protocol details the preparation of muscle samples for proteomics analysis using ultra-high-performance liquid chromatography (UHPLC).
View Article and Find Full Text PDFEffect of Multi-component Exercise Program on Functional Performance in Breast Cancer Survivors.
Asian Pac J Cancer Prev
December 2024
Department of Microbiology, Krishna VishwaVidyapeeth( Krishna Institute of Medical Sciences Deemed to be University), Karad, Maharashtra, India.
Background: Breast surgery, radiation, chemotherapy and modified radical mastectomy (MRM) may cause long-term side effects such as decreased muscle strength, pulmonary function, cardio-respiratory fitness (CRF), altered body fat distribution and poor sleep quality. These short- and long-term repercussions have an enormous effect on physical functioning in this population. The goal of this research was to determine the effect of a multi-component exercise program on functional performance in breast cancer survivors.
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