Pentafluorobenzene: Promising Applications in Diagnostics and Therapeutics.

ACS Appl Bio Mater

Medical Research Center for Bioreaction to Reactive Oxygen Species and Biomedical Science Institute, Core Research Institute (CRI), Kyung Hee University, Seoul 02447, Republic of Korea.

Published: October 2023

AI Article Synopsis

  • Pentafluorobenzene (PFB) is a type of aromatic fluorine compound crucial in various chemical and biological applications, particularly in drug delivery and bioactive materials.
  • The review highlights recent advancements in the use of PFB-derived molecules for diagnostic applications and explores PFB's potential in theragnostics, which combines therapy and diagnostics.
  • It discusses various mechanisms and strategies that utilize PFBs to enhance material properties and facilitate different reactions, supporting its role as a significant tool in research and development.

Article Abstract

Pentafluorobenzene (PFB) represents a class of aromatic fluorine compounds employed exclusively across a spectrum of chemical and biological applications. PFBs are credited with developing various chemical synthesis techniques, networks and biopolymers, bioactive materials, and targeted drug delivery systems. The first part of this review delves into recent developments in PFB-derived molecules for diagnostic purposes. In the latter segment, PFB's role in the domain of theragnostic applications is discussed. The review elucidates different mechanisms and interaction strategies applied in leveraging PFBs to formulate diagnostic and theragnostic tools, substantiated by proper examples. The utilization of PFBs emerges as an enabler, facilitating manifold reactions, improving materials' properties, and even opening avenues for explorative research.

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Source
http://dx.doi.org/10.1021/acsabm.3c00676DOI Listing

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Medical Research Center for Bioreaction to Reactive Oxygen Species and Biomedical Science Institute, Core Research Institute (CRI), Kyung Hee University, Seoul 02447, Republic of Korea.

Article Synopsis
  • Pentafluorobenzene (PFB) is a type of aromatic fluorine compound crucial in various chemical and biological applications, particularly in drug delivery and bioactive materials.
  • The review highlights recent advancements in the use of PFB-derived molecules for diagnostic applications and explores PFB's potential in theragnostics, which combines therapy and diagnostics.
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