AI Article Synopsis
- * Conducted as a double-blind clinical trial with 148 patients, the study assessed the impact of these medications given 30 minutes before surgery ended.
- * Results indicated that dexmedetomidine was most effective in lowering shivering, as well as reducing heart rate and mean arterial pressure; however, it also prolonged recovery time, highlighting a trade-off in its use.
Article Abstract
Postoperative shivering is one of the most common complications of surgeries. The current research compared the effects of ketamine, granisetron, and dexmedetomidine on reducing postoperative shivering after general anesthesia. This double-blind clinical trial enrolled 148 patients (39.08 ± 5.99 years old) who had been admitted to Vali-Asr Hospital of Arak, Iran in 2019-2021. The study drugs, including dexmedetomidine, ketamine, granisetron and normal saline, were administered in corresponding groups 30 minutes before the end of surgery. The results showed that dexmedetomidine reduced mean arterial pressure and heart rate in patients. The lowest incidence of shivering was observed in the dexmedetomidine group and it increased the duration of recovery. Overall, dexmedetomidine is recommended to reduce postoperative shivering after general anesthesia, but the increase in duration of recovery should be considered.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10710286 | PMC |
| http://dx.doi.org/10.4103/2045-9912.374389 | DOI Listing |
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Article Synopsis
- The study aimed to compare the effectiveness of intravenous dexmedetomidine versus a combination of low-dose ketamine and dexmedetomidine for extending spinal anesthesia in lower limb orthopedic surgeries.
- Conducted on 60 patients, the study divided them into two groups: one receiving only dexmedetomidine (Group D) and the other receiving a mix of ketamine and dexmedetomidine (Group LKD).
- Results showed similar anesthesia duration between groups, but Group D experienced more hypotension episodes, while Group LKD required less tramadol post-surgery.
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