Background: Primary central nervous system tumors are a leading cause of death and disability amongst pediatric cancer patients. Akron Children's Hospital published data in 2018 on response time for brain tumor diagnosis and implemented components of an established program to decrease diagnostic delays and thereby reduce tumor- and treatment-related morbidities. This study evaluates if there was an improvement in the total diagnostic interval (TDI, time from symptom onset to diagnosis) after provider education. During the study, the COVID-19 pandemic forced alterations in care delivery. The impact this had on the TDI was also assessed.
Methods: A retrospective chart review was performed, and patients were separated into 2008-2017 (historical) and 2018-2021 (posteducation) groups to assess the effect of educational interventions on TDI. The posteducation cohort was analyzed separately to assess the impact of COVID-19 pandemic.
Results: The 85 patients studied in the post-education group showed a median TDI of 31 days. Though not statistically significant ( = .939), this represents an 11-day decrease in median TDI compared to the historical group (42 days). In addition, the posteducation group showed an increase in the average number of healthcare provider visits (HCP, 2.4 historical to 3.2 posteducation, = .009). The pre-COVID-19 group (median TDI 43.5 days) did not differ statistically from the post-COVID-19 group (30-day median TDI).
Conclusion: The nonsignificant decrease in TDI and concurrent increase in HCP visits after implementation of education suggests a potential gap amongst providers in working-up primary CNS tumors. These results will influence expansion of education to further improve TDI.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10502781 | PMC |
http://dx.doi.org/10.1093/nop/npad024 | DOI Listing |
Diabetol Metab Syndr
January 2025
Department of Ophthalmology, Shengli Clinical College of Fujian Medical University; Fuzhou University Affiliated Provincial Hospital, School of Medicine, Fuzhou University, Fuzhou, Fujian, China.
Background: Prior studies on the link between socioeconomic status (SES) and diabetic microvascular complications have been inconclusive. This study aimed to explore whether SES is associated with the risk of diabetic retinopathy (DR), nephropathy (DN) and diabetic peripheral neuropathy (DPN) using large prospective cohort.
Methods: SES was evaluated using education attainment (individual level), household income (household level), and Townsend deprivation index (TDI, neighborhood level).
Clin Oral Investig
November 2024
Restorative Dentistry Department, School of Dentistry, Federal University of Minas Gerais, R. Prof. Moacir Gomes de Freitas, 688, Pampulha, Belo Horizonte, MG, 31270-901, Brazil.
Cardiovasc Diagn Ther
October 2024
Vanderbilt Institute of Global Health, Vanderbilt University Medical Centre, Nashville, TN, USA.
J Echocardiogr
October 2024
Department of Cardiovascular Sciences, Katholieke Universiteit Leuven, Oude Markt 13, 3000, Louvain, Belgium.
J Pediatr Endocrinol Metab
October 2024
Pediatric Endocrinology, Diabetes, Endocrinology and Metabolism Pediatric Unit (DEMPU), Department of Pediatrics, Faculty of Medicine, Cairo University, Cairo, Egypt.
Objectives: To assess the role of Cardiotrophin-1 (CT-1) and echocardiography in early detection of subclinical Diabetic Cardiomyopathy (DCM) in children with type 1 Diabetes Mellitus (T1D).
Methods: This case-control study included two groups of children and adolescents aged between 7 and 18. Group (1) included forty patients with T1D (duration > 5 years) regularly followed at the children's hospital of Cairo University, and Group (2) included forty age and sex-matched healthy subjects as a control group.
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