Beta arrestins are a family of adaptor proteins that help in the regulation of signaling and trafficking of various G protein coupled receptors (GPCRs). Six oxadiazole derivatives taken from literature are analyzed for anti-cancer properties. The toxicity profiles of all the drugs were similar to Tamoxifen used as control. Data shows that compounds 2, 4, and 6 exhibited comparably significant molecular interactions with the cancerous protein for further consideration.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10504516 | PMC |
| http://dx.doi.org/10.6026/97320630019111 | DOI Listing |
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