AI Article Synopsis

  • The study assessed the effectiveness and safety of a new hydrolyzed collagen injection device (CHondroGrid) for treating rotator cuff tendinopathy in 71 patients.
  • Patients received two injections spaced about two weeks apart, with outcomes measured pre-treatment, 1 month, and 6 months post-treatment.
  • Results showed significant pain relief and improvement in shoulder function, with no reported adverse events, indicating CHondroGrid is a promising treatment option.

Article Abstract

Background: The purpose of the present observational multicentric prospective study was to evaluate the efficacy and safety of a new infiltration device (CHondroGrid, Bioteck S.p.A, Arcugnano, Italy) based on hydrolyzed collagen in the treatment of rotator cuff tendinopathy.

Methods: Seventy-one patients (53.3 ± 11.6 years old) affected by rotator cuff tendinopathy were treated in 2021 with two subacromial injections of CHondroGrid at 13 ± 2.9 days apart. The outcomes measured were the visual analog scale (VAS) score (in movement, during the night, and at rest), the Constant Score, the Simple Shoulder Test, and patient satisfaction. The outcome variables were measured before each injection, at 1 month and at 6 months after the last injection.

Results: The treatment was significantly effective from the first injection and up to the six-month follow-up. At the last follow-up, the VAS score on movement had improved by 71% ( < .001), while the VAS score at rest and during the night had ameliorated by 91% and 87%, respectively ( < .001). The Constant Score and Simple Shoulder Test improved by 32% and 61%, respectively ( < .001). No adverse events were reported.

Conclusions: CHondroGrid resulted in a safe and effective treatment in pain relief and for the functional recovery of rotator cuff tendinopathy.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499841PMC
http://dx.doi.org/10.1016/j.jseint.2023.06.009DOI Listing

Publication Analysis

Top Keywords

rotator cuff
12
hydrolyzed collagen
8
treatment rotator
8
cuff tendinopathy
8
observational multicentric
8
multicentric prospective
8
prospective study
8
vas score
8
score movement
8
subacromial injection
4

Similar Publications

Ultrasound radiomics predict the success of US-guided percutaneous irrigation for shoulder calcific tendinopathy.

Jpn J Radiol

January 2025

Artificial Intelligence and Translational Imaging (ATI) Lab, Department of Radiology, School of Medicine, University of Crete, Voutes Campus, Heraklion, Greece.

Objective: Calcific tendinopathy, predominantly affecting rotator cuff tendons, leads to significant pain and tendon degeneration. Although US-guided percutaneous irrigation (US-PICT) is an effective treatment for this condition, prediction of patient' s response and long-term outcomes remains a challenge. This study introduces a novel radiomics-based model to forecast patient outcomes, addressing a gap in the current predictive methodologies.

View Article and Find Full Text PDF

Effects of Biceps Rerouting on In Vivo Glenohumeral Kinematics in the Treatment of Large-to-Massive Rotator Cuff Tears.

Am J Sports Med

January 2025

Department of Sports Medicine, Shanghai Sixth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Background: Arthroscopic repair with the biceps rerouting (BR) technique has been determined to lead to promising clinical and biomechanical outcomes for treating large-to-massive rotator cuff tears (LMRCTs). However, the in vivo effects of BR on glenohumeral kinematics during functional shoulder movements have not been fully elucidated.

Purpose: To investigate whether BR provides a better restoration of shoulder kinematics compared with conventional rotator cuff repair (RCR).

View Article and Find Full Text PDF

Reconstruction of the Superior Capsule Using Peroneus Longus Tendon Graft Combined With Transposition of Biceps Tendon for Irreparable Massive Rotator Cuff Tears.

Am J Sports Med

January 2025

Sports Medicine Center, Department of Orthopaedic Surgery/Orthopaedic Research Institute, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Background: Traditional superior capsular reconstruction (SCR) with biceps tendon transposition (TB) alone for irreparable massive rotator cuff tears (IMRCTs) has demonstrated a high retear rate, highlighting the need for alternative approaches. Therefore, SCR using a peroneus longus tendon graft (PLG) combined with TB (PLG-TB) should be clinically studied.

Purpose: To compare the clinical and radiological outcomes of SCR using the PLG-TB technique versus the TB technique alone for IMRCT.

View Article and Find Full Text PDF

Background: For patients with osteoporosis and rotator cuff tears, there is still no consensus on current treatment methods. The material, structure, and number of anchors have important effects on the repair outcome.

Purpose: To investigate the use of chitosan quaternary ammonium salt-coated nickel-titanium memory alloy (NTMA) anchors to treat rotator cuff injury in shoulders with osteoporosis in a rabbit osteoporosis model.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!