Cancer growing in hollow organs has become a serious threat to human health. The accurate T-staging of hollow organ cancers is a major concern in the clinic. With the rapid development of medical imaging technologies, radiomics has become a reliable tool of T-staging. Due to similar growth characteristics of hollow organ cancers, radiomics studies of these cancers can be used as a common reference. In radiomics, feature-based and deep learning-based methods are two critical research focuses. Therefore, we review feature-based and deep learning-based T-staging methods in this paper. In conclusion, existing radiomics studies may underestimate the hollow organ wall during segmentation and the depth of invasion in staging. It is expected that this survey could provide promising directions for following research in this realm.
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http://dx.doi.org/10.3389/fonc.2023.1191519 | DOI Listing |
Med Acupunct
December 2024
Department of Science in Korean Medicine, Graduate School, Kyung Hee University, Seoul, Republic of Korea.
Background: Combinations of and points are widely used to treat internal organ issues in both clinical practice and scientific research. We investigated the selection patterns of and points used in clinical trials. We also conducted a network analysis to identify the most common combinations of these acupoints.
View Article and Find Full Text PDFJ Colloid Interface Sci
December 2024
Department of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang, Liaoning Province 110016, PR China. Electronic address:
Photodynamic therapy (PDT) has witnessed remarkable progress in recent years owing to its specific properties. Given that the antioxidation system of tumor microenvironment (TME) adversely affects treatment outcomes, powerful TME modulators can significantly resolve the limitation of PDT. Herein, we developed a PEG-modified Cu-doped hollow mesoporous carbon nanozyme (CHC-PEG) and loaded insoluble photosensitizer IR780 into its pores and cavities to construct the multifunctional nano-system IR780/CHCP.
View Article and Find Full Text PDFActa Biomater
December 2024
Department of Sport and Motion Science, University of Stuttgart, Stuttgart, Germany; Stuttgart Center for Simulation Science, University of Stuttgart, Stuttgart, Germany.
The urinary bladder is a hollow organ that undergoes significant deformation as it receives, stores, and releases urine. To understand the organ mechanics, it is necessary to obtain information about the material properties of the tissues involved. In displacement-controlled tensile tests, tissue samples are mounted on a device that applies stretches to the tissue in one or more directions, resulting in a specific stress response.
View Article and Find Full Text PDFQuant Imaging Med Surg
December 2024
Department of Minimally Invasive Tumor Therapies Center, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, and Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China.
Background And Objective: In patients diagnosed with bladder cancer (BC), muscle-invasive bladder cancer (MIBC) accounts for 25%, including tumors invading the intrinsic muscle layer (T2), surrounding tissues of the bladder (T3), or adjacent pelvic organs/structures (T4). Cryoablation promises to be a novel interventional oncology technique, which effectively induces cellular destruction through freezing and thawing cycles. In addition to the direct tumor-killing effect, it also has a tumor-immune effect.
View Article and Find Full Text PDFAdv Mater
December 2024
School of Materials Science and Engineering, Peking University, Beijing, 100871, P. R. China.
In situ measurement of nitric oxide (NO) in living tissue and single cells is highly important for achieving a profound comprehension of cellular functionalities and facilitating the precise diagnosis of critical diseases; however, the progress is greatly hindered by the weak affinity of ultratrace concentration NO in cellular environment toward electrocatalysts. Herein, a new strategy is reported for precisely constructing orbital coupled dual-atomic sites to enhance the affinity between the metal atomic sites and NO on a class of N-doped hollow carbon matrix dual-atomic sites Co─Ni (CoNi-NC) for greatly boosting electrocatalytic NO performance. The as-synthesized CoNi-NC demonstrates a substantially higher current density than Ni-NC and Co-NC, coupled with exceptional stability with a negligible degradation rate of 0.
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