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http://dx.doi.org/10.1111/ijd.16827DOI Listing

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"Kaposi varicelliform eruption" (KVE), also known as "eczema herpeticum," refers to a rare widespread skin infection. The primary causal agent is thought to be the herpes simplex virus (HSV). Though common in patients with underlying skin dermatosis, systemic immunosuppression can at times lead to KVE.

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Article Synopsis
  • A case report discusses a 35-year-old male with a history of atopic dermatitis who developed a severe herpes simplex virus-1 (HSV-1) related skin condition called Kaposi varicelliform eruption (KVE) after a recent SARS-CoV-2 infection.
  • The patient's skin condition involved widespread vesicles and pustules that rapidly progressed over four months, and laboratory tests confirmed he was positive for HSV-1 with elevated IgE levels and decreased immune cell counts.
  • Treatment with valaciclovir and other medications led to significant improvement, with the skin lesions resolving completely within a week, emphasizing the risk of severe viral eruptions in patients with existing skin conditions following viral infections.
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[Erythroderma Complicated With Kaposi Varicelliform Eruption:Report of One Case].

Zhongguo Yi Xue Ke Xue Yuan Xue Bao

October 2024

Department of Dermatology, Second Hospital of Shanxi Medical University,Taiyuan 030001,China.

Kaposi varicelliform eruption (KVE) refers to an infectious skin disease that occurs after infection with herpes simplex virus,Coxsackie virus,or other viruses on the basis of preexisting skin diseases,commonly observed in the patients with eczema.It is rare for the patients with erythroderma to be complicated with KVE,and symptoms are often atypical,which pose a challenge to the diagnosis and treatment.This article reports a case of erythroderma complicated with KVE,aiming to raise awareness of clinicians in treating this disease.

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Article Synopsis
  • * The study compared the effectiveness and safety of upadacitinib (UPA) and dupilumab (DUPI) in adolescents and adults with moderate-to-severe AD over 16 weeks, with UPA showing better results in reducing skin severity and itching.
  • * UPA was found to be significantly more effective than DUPI in achieving the treatment goals, with no new safety concerns reported during the study.
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