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Phylogenomic analysis of Stylops reveals the evolutionary history of a Holarctic Strepsiptera radiation parasitizing wild bees.
Mol Phylogenet Evol
June 2024
Department of Zoology, Swedish Museum of Natural History, P. O. Box 50007, SE-104 05 Stockholm, Sweden; Department of Zoology, Faculty of Science, Stockholm University, SE-106 91 Stockholm, Sweden. Electronic address:
Holarctic Stylops is the largest genus of the enigmatic insect order Strepsiptera, twisted winged parasites. Members of Stylops are obligate endoparasites of Andrena mining bees and exhibit extreme sexual dimorphism typical of Strepsiptera. So far, molecular studies on Stylops have focused on questions on species delimitation.
View Article and Find Full Text PDFCoupling allows robust mammalian redox circadian rhythms despite heterogeneity and noise.
Heliyon
January 2024
Institute for Theoretical Biology - Humboldt Universität zu Berlin and Charité Universitätsmedizin Berlin, Philippstraße 13, 10115 Berlin, Germany.
Circadian clocks are endogenous oscillators present in almost all cells that drive daily rhythms in physiology and behavior. There are two mechanisms that have been proposed to explain how circadian rhythms are generated in mammalian cells: through a transcription-translation feedback loop (TTFL) and based on oxidation/reduction reactions, both of which are intrinsically stochastic and heterogeneous at the single cell level. In order to explore the emerging properties of stochastic and heterogeneous redox oscillators, we simplify a recently developed kinetic model of redox oscillations to an amplitude-phase oscillator with 'twist' (period-amplitude correlation) and subject to Gaussian noise.
View Article and Find Full Text PDFDeferring diagnostic evaluation for suspected deep venous thrombosis using a single dose of anticoagulant: Real-world data from a regionwide care pathway.
Eur J Intern Med
April 2024
Department of Internal Medicine, Zuyderland Medical Center, Sittard/Heerlen, the Netherlands. Electronic address:
Background: Patients with suspected deep venous thrombosis (DVT) are typically referred to the emergency department (ED) for immediate evaluation. However, this often contributes to ED overcrowding and necessitates round-the-clock sonographic examinations. Therefore, we implemented a regionwide care pathway for deferring diagnostic workup of suspected DVT until the following day.
View Article and Find Full Text PDFAre circadian amplitudes and periods correlated? A new twist in the story.
F1000Res
April 2024
Institute for Theoretical Biology, Humboldt Universität zu Berlin and Charité Universitätsmedizin Berlin, Philippstr. 13, 10115 Berlin, Germany.
Three parameters are important to characterize a circadian and in general any biological clock: period, phase and amplitude. While circadian periods have been shown to correlate with entrainment phases, and clock amplitude influences the phase response of an oscillator to pulse-like zeitgeber signals, the co-modulations of amplitude and periods, which we term , have not been studied in detail. In this paper we define two concepts: refers to amplitude-period correlations arising in ensembles of self-sustained, limit cycle clocks in the absence of external inputs, and refers to the co-modulation of an individual clock's amplitude and period in response to external zeitgebers.
View Article and Find Full Text PDFTwist Around the Clock!
Eur J Vasc Endovasc Surg
December 2023
Department of Radiology, University Hospital of Strasbourg, Strasbourg, France.
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