The Oscillatoria sp., a blue-green alga or cyanobacterium, consists of about 305 species distributed globally. Cyanobacteria are prokaryotes possessing several secondary metabolites that have industrial and biomedical applications. Particularly, the published reviews on Oscillatoria sp. have not recorded any pharmacology, or possible details, while the detailed chemical structures of the alga are reported in the literature. Hence, this study considers pertinent pharmacological activities of the plethora of bioactive components of Oscillatoria sp. Furthermore, the metallic nanoparticles produced with Oscillatoria sp. were documented for plausible antibacterial, antifungal, antioxidant, anticancer, and cytotoxic effects against several cultured human cell lines. The antimicrobial activities of solvent extracts of Oscillatoria sp. and the biotic activities of its derivatives, pyridine, acridine, fatty acids, and triazine were structurally described in detail. To understand the connotations with research gaps and provide some pertinent prospective suggestions for further research on cyanobacteria as potent sources of pharmaceutical utilities, attempts were documented. The compounds of Oscillatoria sp. are a potent source of secondary metabolites that inhibit the cancer cell lines, in vitro. It could be expected that by holistic exploitation, the natural Oscillatoria products, as the source of chemical varieties and comparatively more potent inhibitors, would be explored against pharmacological activities with the integument of SARs.
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http://dx.doi.org/10.1007/s00210-023-02719-8 | DOI Listing |
Mar Pollut Bull
December 2024
Faculty of Science and Natural Resources, Universiti Malaysia Sabah, Kota Kinabalu, Sabah, Malaysia.
Microcystins are generated by diverse cyanobacteria in shrimp ponds marked by high nutrient levels. The study examined microcystin-leucine arginine (MC-LR) in the pond water, gills, hepatopancreas, and muscle of shrimp (Litopenaeus vannamei) from shrimp ponds on the northern coast of East Java and its effects on their histological structures. In shrimp ponds dominated by cyanobacteria particularly Microcystis and Oscillatoria, MC-LR levels were high.
View Article and Find Full Text PDFMar Drugs
November 2024
Department of Marine Biology and Biotechnology, University of Gdańsk, M. J. Piłsudskiego 46, PL-81378 Gdynia, Poland.
Aeruginosins (AERs) are one of the most common classes of cyanobacterial peptides synthesised through a hybrid non-ribosomal peptide synthase/polyketide synthase pathway. They have been found in , , /, and The presence of AER in isolated from the Curonian Lagoon was reported for the first time in our previous work. Here, the structure of aeruginosin 525 (AER525), isolated from sp.
View Article and Find Full Text PDFToxicon
January 2025
Key Laboratory of Lake and Watershed Science for Water Security, Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences, Nanjing, 210008, China; State Key Laboratory of Lake Science and Environment, Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences, Nanjing, 210008, China.
As global warming and water eutrophication, the multiple proliferation of harmful cyanobacteria can form algal blooms and cause serious ecological problems. In recent years, the large-scale and persistent cyanobacterial blooms occur frequently worldwide and have attracted widespread attention due to the harmful impacts. Among these harmful bloom-forming cyanobacteria, the ecological and toxicological impacts of planktonic cyanobacteria have been extensively studied.
View Article and Find Full Text PDFJ Phycol
December 2024
Faculty of Biology and Biotechnology, Department of Biotechnology, Al-Farabi Kazakh National University, Almaty, Kazakhstan.
Allelopathy plays a crucial role in shaping phytoplankton community dynamics and diversity. It influences competition between photoautotrophs for resources and affects species succession in aquatic ecosystems. This article evaluates the allelopathic activity of cyanobacteria isolated from Lake Tuzkol, Kazakhstan.
View Article and Find Full Text PDFPlants (Basel)
October 2024
K.A. Timiryazev Institute of Plant Physiology, Russian Academy of Sciences, Botanicheskaya Street 35, Moscow 127276, Russia.
Cyanobacterial pigments have attracted considerable attention in industry due to their bioactive potential and natural origin. In the present study, the growth dynamics and pigment composition, in terms of chlorophyll , total carotenoids and phycobiliprotein content, of four cyanobacterial strains isolated from thermal springs, namely CZS 2201, CZS 2205, TSZ 2203, and sp. CZS 2204, were investigated.
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