Med Klin Intensivmed Notfmed
Zentrum für Notaufnahme, Krankenhaus der Barmherzigen Brüder Trier, Medizincampus Trier der Universitätsmedizin Mainz, Trier, Deutschland.
Published: December 2023
Patients with potential or proven cardiovascular diseases represent a relevant proportion of the total spectrum in the emergency department. Their monitoring for cardiovascular surveillance until the diagnostics and acute treatment are initiated, often poses an interdisciplinary and interprofessional challenge, because resources are limited, nevertheless a high level of patient safety has to be ensured and the correct procedure has a major prognostic significance. This consensus paper provides an overview of the practical implementation, the modalities of monitoring and the application in a selection of cardiovascular diagnoses. The article provides specific comments on the clinical presentations of acute coronary syndrome, acute heart failure, cardiogenic shock, hypertensive emergency events, syncope, acute pulmonary embolism and cardiac arrhythmia. The level of evidence is generally low as no randomized trials are available on this topic. The recommendations are intended to supplement or establish local standards and to assist all physicians, nursing personnel and the patients to be treated in making decisions about monitoring in the emergency department.
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http://dx.doi.org/10.1007/s00063-023-01069-w | DOI Listing |
Am J Alzheimers Dis Other Demen
March 2025
Pathology Department, Chongqing UniversityCentral Hospital, Chongqing Emergency Medical Center, Chongqing, China.
White matter hyperintensity (WMH) is associated with cognitive impairment. In this study, 79 patients with WMH from hospital 1 were randomly divided into a training set (62 patients) and an internal validation set (17 patients). In addition, 29 WMH patients from hospital 2 were used as an external validation set.
View Article and Find Full Text PDFActa Biomater
March 2025
Department of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China. Electronic address:
Traditional methods of plasmid delivery, including viral vectors, lipofection, and electroporation, are widely used for gene editing but have limitations, such as cellular toxicity, limited transfection efficiency in primary cells, and nonspecific side effects. Here, we report the development of nucleus pulposus cell (NPC)-mimicking nanoparticles (HIF1A@NNP) with an NPC membrane as the shell and pcDNA3.1-rHIF1A encapsulated in the core via extrusion.
View Article and Find Full Text PDFBr J Oral Maxillofac Surg
December 2024
Department of Radiodiagnosis and Imaging, LNMC & JK Hospital, Bhopal, India.
This systematic review aimed to evaluate the application of artificial intelligence (AI) in the identification of temporomandibular joint (TMJ) disc position in normal or temporomandibular joint disorder (TMD) individuals using magnetic resonance imaging (MRI). Database search was done in Pub med, Google scholar, Semantic scholar and Cochrane for studies on AI application to detect TMJ disc position in MRI till September 2023 adhering PRISMA guidelines. Data extraction included number of patients, number of TMJ/MRI, AI algorithm and performance metrics.
View Article and Find Full Text PDFJ Arthroplasty
February 2025
Department of Orthopedic Surgery, NYU Langone Health, New York, New York.
Background: Obesity and diabetes mellitus (DM) pose challenges for patients undergoing total knee arthroplasty (TKA). Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have emerged as agents for weight and DM management, but they affect multiple organ systems. Outcomes, trends, and demographics for perioperative GLP-1RA use in patients with TKA are not well understood.
View Article and Find Full Text PDFSci Total Environ
March 2025
Division of Pulmonary Medicine, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; School of Respiratory Therapy, College of Medicine, Taipei Medical University, Taipei, Taiwan; National Heart and Lung Institute, Imperial College London, London, UK; Cell Physiology and Molecular Image Research Center, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan. Electronic address:
Introduction: This systematic review examines how extreme temperatures impact Chronic Obstructive Pulmonary Disease (COPD) morbidity and mortality, focusing on identifying vulnerable subpopulations.
Methods: We conducted a systematic literature search from January 1, 2000, to November 6, 2024, across databases like PubMed, MEDLINE and EMBASE, Web of Science, and Scopus, focusing on observational studies that quantitatively defined extreme temperatures and their impacts on COPD morbidity and mortality. Out of 3140 records, 25 studies met the inclusion criteria.
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