Deep eutectic solvent-based modified quick, easy, cheap, effective, rugged, and safe extraction combined with solidification of floating organic droplet-dispersive liquid-liquid microextraction of some pesticides from canola oil followed by gas chromatography analysis.

Herein, a modified quick, easy, cheap, effective, rugged, and safe extraction was developed based on deep eutectic solvent for the extraction of several pesticides from canola oil samples. In this work, first, different sorbents were selected to remove the sample interferences, and the composition of the sorbents was optimized by simplex centroid design. The extracted analytes were more concentrated by solidification of floating deep eutectic solvent droplet-dispersive liquid-liquid microextraction. Low limits of detection (0.15-0.23 ng/g) and quantification (0.49-0.76 ng/g), high extraction recoveries (74-87%) and enrichment factors (224-263), and good repeatability (relative standard deviation equal to or less than 5.1 and 4.7% for intra- and interday precisions, respectively) were achieved using the proposed method. The suggested approach was used for the quantification of the analytes in different canola oil samples. Additionally, the effects of microwave irradiations exposure and sonication in decontamination of the samples were evaluated. In this method, there was no need for centrifugation and toxic solvents. Also, effective extraction of the analytes and minimizing interferences were achieved through the use of various sorbents.