AI Article Synopsis
- A rare case of a submandibular gland epidermoid cyst in a 49-year-old female transformed into squamous cell carcinoma (SCC), which is extremely uncommon and previously unreported in literature.
- Diagnosis was confirmed through clinical examination, cytology, and imaging, followed by intraoperative frozen section and histopathological examination.
- The patient underwent complete surgical excision with a clear margin and neck dissection, and there were no signs of recurrence during a one-year follow-up.
Article Abstract
Rationale: Submandibular gland epidermoid cyst is extremely rare and malignant transformation into squamous cell carcinoma (SCC) is even rarer. No such case report is published.
Patient Concerns: A 49-year-old female reported with a large, slowly growing left-sided neck swelling present for two years. Her primary concern was large swelling.
Diagnosis: Clinical finding, cytology and imaging were suggestive of 'Epidermoid Cyst of Submandibular Gland'. Intraoperative frozen section and post-operative definitive histopathological examination (HPE) revealed malignant transformation into SCC.
Treatment: In toto surgical excision was performed. Once the frozen section HPE confirmed transformation into SCC, clearance of 4-6 mm margin and modified supraomohyoid neck dissection was completed.
Outcome: No sign of recurrence on 1-year postoperative follow-up.
Take-away Lesson: This case is unique of its kind without any previous literature report. In case of large and rapidly growing submandibular gland lesion, possibility of malignant transformation should not be overruled.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499289 | PMC |
| http://dx.doi.org/10.4103/ams.ams_167_22 | DOI Listing |
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