Point clouds have evolved into one of the most important data formats for 3D representation. It is becoming more popular as a result of the increasing affordability of acquisition equipment and growing usage in a variety of fields. Volumetric grid-based approaches are among the most successful models for processing point clouds because they fully preserve data granularity while additionally making use of point dependency. However, using lower order local estimate functions to close 3D objects, such as the piece-wise constant function, necessitated the use of a high-resolution grid in order to capture detailed features that demanded vast computational resources. This study proposes an improved fused feature network as well as a comprehensive framework for solving shape classification and segmentation tasks using a two-branch technique and feature learning. We begin by designing a feature encoding network with two distinct building blocks: layer skips within, batch normalization (BN), and rectified linear units (ReLU) in between. The purpose of using layer skips is to have fewer layers to propagate across, which will speed up the learning process and lower the effect of gradients vanishing. Furthermore, we develop a robust grid feature extraction module that consists of multiple convolution blocks accompanied by max-pooling to represent a hierarchical representation and extract features from an input grid. We overcome the grid size constraints by sampling a constant number of points in each grid using a simple K-points nearest neighbor (KNN) search, which aids in learning approximation functions in higher order. The proposed method outperforms or is comparable to state-of-the-art approaches in point cloud segmentation and classification tasks. In addition, a study of ablation is presented to show the effectiveness of the proposed method.
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http://dx.doi.org/10.3389/fncom.2023.1204445 | DOI Listing |
Life Sci
December 2024
College of Medicine and Health Sciences, China Three Gorges University, Yichang 443002, China; Hubei Key Laboratory of Tumor Microenvironment and Immunotherapy, China Three Gorges University, Yichang 443002, China. Electronic address:
Background: Fibroblast Growth Factor 21 (FGF21) is a naturally occurring peptide hormone involved in the regulation of glycolipid metabolism, and it shows promise as a potential treatment for type 2 diabetes mellitus (T2DM). However, the short half-life and poor pharmacokinetics of native FGF21 limit its efficacy in reducing hyperglycemia in vivo. Therefore, maintaining stable and sustained blood concentrations of FGF21 is crucial for its role as an effective regulator of glycolipid metabolism in vivo.
View Article and Find Full Text PDFWorld J Gastroenterol
December 2024
School of Computer Science Technology, Changchun University, Changchun 130022, Jilin Province, China.
Background: Wireless capsule endoscopy (WCE) has become an important noninvasive and portable tool for diagnosing digestive tract diseases and has been propelled by advancements in medical imaging technology. However, the complexity of the digestive tract structure, and the diversity of lesion types, results in different sites and types of lesions distinctly appearing in the images, posing a challenge for the accurate identification of digestive tract diseases.
Aim: To propose a deep learning-based lesion detection model to automatically identify and accurately label digestive tract lesions, thereby improving the diagnostic efficiency of doctors, and creating significant clinical application value.
3D Print Addit Manuf
December 2024
Institute of Materials Science and Engineering, Faculty of Mechanical Engineering, Lodz University of Technology, Łódź, Poland.
Fused Filament Fabrication (FFF) printing is one of the most all-purpose manufacturing techniques, allowing many complicated parts to be obtained at lower cost. This is especially important in prosthetics, where more complex prostheses, especially of a hand, can cause enormous expense. However, providing the full functionality of a prosthesis often requires combining materials with different properties, such as rigidity and flexibility.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
Key Laboratory of Molecular Microbiology and Technology, Ministry of Education, TEDA Institute of Biological Sciences and Biotechnology, Nankai University, TEDA, Tianjin 300457, PR China; Tianjin Key Laboratory of Microbial Functional Genomics, Tianjin 300457, PR China. Electronic address:
The robustness and catalytic activity of superoxide dismutase (SOD) are still the main factors limiting their application in industrial fields. This study aims to further improve the properties of a natural thermophilic iron/manganese dual-domain SOD (Fe/Mn-SODA fused with N-terminal polypeptide) from Geobacillus thermodenitrificans NG80-2 (GtSOD) by modifying its each domain using in-depth in silico prediction analysis as well as protein engineering. First, computational analysis of the N-terminal domain and GtSODA domain was respectively performed by using homologous sequence alignment and virtual mutagenesis.
View Article and Find Full Text PDFInt J Pharm
December 2024
Beijing Institute of Radiation Medicine, Beijing 100850, China. Electronic address:
Cannabidiol (CBD) is widely used to alleviate the syndromes of epilepsy. However, the marketed oral CBD formulation has the prominent first-pass effect. Here, a cannabidiol-loaded hollow suppository (CHS) was developed using three-dimensional (3D) printing technology.
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