Previous simulation studies of cavity based free electron lasers (FELs) have utilised models which average the optical field in the FEL interaction over an integer number of radiation wavelengths. In this paper, two unaveraged simulation codes, OPC and Puffin, are combined to enable modelling, for the first time, of a cavity based FEL at the sub-wavelength scale. This enables modelling of effects such as coherent spontaneous emission from the electron beam and sub-wavelength cavity length detuning. A cavity FEL operating in the mid-infrared is modelled and it is shown that, for small sub-wavelength cavity detunings, the FEL can preferentially lase at the third harmonic of the fundamental FEL wavelength. This novel result suggests other modes of operation may be possible and opens up cavity-based FEL operation to investigation of further, potentially useful, modes of operation.
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http://dx.doi.org/10.1364/OE.494481 | DOI Listing |
Mikrochim Acta
January 2025
Department of Analytical Chemistry, Faculty of Pharmacy, "Iuliu Hațieganu" University of Medicine and Pharmacy, 4 Pasteur Street, 400349, Cluj-Napoca, Romania.
A label-free, flexible, and disposable aptasensor was designed for the rapid on-site detection of vancomycin (VAN) levels. The electrochemical sensor was based on lab-printed carbon electrodes (C-PE) enriched with cauliflower-shaped gold nanostructures (AuNSs), on which VAN-specific aptamers were immobilized as biorecognition elements and short-chain thiols as blocking agents. The AuNSs, characterized by scanning electron microscopy (SEM) and atomic force microscopy (AFM), enhanced the electrochemical properties of the platform and the aptamer immobilization active sites.
View Article and Find Full Text PDFJ Colloid Interface Sci
April 2025
State Key Laboratory of Pulp and Paper Engineering, South China University of Technology, Guangzhou 510640, China. Electronic address:
Conventional light-driven antimicrobial strategies of zinc oxide (ZnO) are limited by inadequate illumination in dark environments. In this study, carboxylated cellulose nanocrystals (MCNC) mediated flower-like ZnO (C@Z) with self-promoted reactive oxygen species release under dark is fabricated. The adsorption of Zn ions on MCNC prompts the growth of ZnO along the (002) crystal plane, forming a flower-like hybrid with superior dispersibility and oxygen vacancies compared to MCNC-free ZnO, which exposes the (100) plane.
View Article and Find Full Text PDFEnviron Res
January 2025
School of Environment and Energy Engineering, Anhui Jianzhu University, Hefei, 230601, China.
The efficient degradation of SAs is a significant challenge for the treatment of wastewater. To address this, the FeS@BC was prepared by calcining a mixture of pyrite and biomass, and used to activate peroxydisulfate (PDS) to degrade sulfadiazine (SDZ). The effect of carbon sources (wheat straw, rice husk, and corn cob) on catalytic activity of FeS@BC were investigated by Raman spectroscopy, X-ray photoelectron spectroscopy (XPS), total Fe dissolution and free radical quantification.
View Article and Find Full Text PDFViruses
January 2025
Laboratory of Infectious Diseases, College of Veterinary Medicine, Chungnam National University, Daejeon 34134, Republic of Korea.
Self-assembling ferritin nanoparticle technology is a widely used vaccine development platform for enhancing the efficacy of subunit vaccines by displaying multiple antigens on nanocages. The dengue virus (DENV) envelope domain III (EDIII) protein, the most promising antigen for DENV, has been applied in vaccine development, and it is essential to evaluate the relative immunogenicity of the EDIII protein and EDIII-conjugated ferritin to show the efficiency of the ferritin delivery system compared with EDIII. In this study, we optimized the conditions for the expression of the EDIII protein in , protein purification, and refolding, and these optimization techniques were applied for the purification of EDIII ferritin nanoparticles.
View Article and Find Full Text PDFPharmaceutics
January 2025
Department of Horticulture and Life Science, Yeungnam University, Gyeongsan 38541, Republic of Korea.
The development of resistance to traditional antifungal therapies has necessitated the exploration of alternative treatment strategies to effectively manage fungal infections, particularly those induced by (). This research investigates the possibility of integrating silver nanoparticles (AgNPs) with Terbinafine to improve antifungal effectiveness. Terbinafine, while potent, faces challenges with specific fungal strains, highlighting the need for strategies to enhance its treatment efficacy.
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