Retinoblastoma (RB) is a common intraocular malignancy mostly caused by variation of the tumour suppressor gene RB1. In this study, we successfully generated two induced pluripotent stem cell (iPSC) lines from an infant with non-heritable RB. Both cell clones exhibited typical iPSC characteristics with normal karyotypes, consistent pluripotency markers expression and the capability of trilineage differentiation.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.scr.2023.103200 | DOI Listing |
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!