The term "cold agglutinin (CA)" refers to a group of disorders caused by anti-erythrocyte autoantibodies that preferentially bind RBCs at cold temperatures (4°C-18°C). CAs contribute to 10 to 15% of autoimmune hemolytic anemia. We report a case of CAs diagnosed intraoperatively during emergency mitral valve replacement.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284479PMC
http://dx.doi.org/10.4103/aca.aca_78_21DOI Listing

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