Antibiotic resistance is one of the biggest global challenges of the century. Many pathogens have become resistant to antibiotics due to human misuse and effective ones are in short supply. Discovering potential new antibiotic molecules may help to address the current antibiotic shortage. To this end, the Tiny Earth program, which engages students from around the world to discover potential antibiotic producing microbes from the local soil, was utilized. Students collect, screen, and isolate bacteria from their local communities in hopes of addressing the global crisis of antibiotic resistance. One such microbe, , was isolated and screened for antimicrobial activity.
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http://dx.doi.org/10.17912/micropub.biology.000921 | DOI Listing |
Klin Mikrobiol Infekc Lek
June 2023
Department of Clinical Microbiology, Pardubice Hospital, Czech Repubic, e-mail:
Objectives: The use of nonadherent dressings is part of care for chronic wounds. In this paper, we present the results of in vitro activity of several such dressings on bacteria most commonly found in chronic wounds.
Material And Methods: Selected bacterial strains were isolated from chronic wounds of patients in Pardubice Hospital in the period from February to May 2022.
Discov Nano
January 2025
National Nanotechnology Laboratory for Agriculture (LNNA), Embrapa Instrumentação, 1452 XV de Novembro St., São Carlos, SP, 13560-970, Brazil.
Multifunctional membranes applied to biomedical materials become attractive to support the biological agents and increase their properties. In this study, biopolymeric fibers based on polycaprolactone (PCL) and pectin (PEC) were reinforced with faujasite zeolite (FAU) for cloxacillin antibiotic (CLX) loading. FAU with a high specific surface area (347 ± 8 m g), high crystallinity and particles with a diameter of up to 100 nm were produced under optimized synthesis conditions (100 °C/4 h).
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
January 2025
Department of Instrumentation and Control Engineering, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Ciprofloxacin (CIP) is an extensively used broad-spectrum, fluoroquinolone antibiotic used for treating diverse bacterial infections. Effluent treatment plants (ETPs) worldwide lack technologies to detect or remediate antibiotics. CIP reaches the aquatic phase primarily due to inappropriate disposal practices, lack of point-of-use sensing, and preloaded activated charcoal filter at ETPs.
View Article and Find Full Text PDFInt Microbiol
January 2025
Phytopathology Unit, Department of Plant Protection, Ecole Nationale d'Agriculture de Meknès, Km 10, Rte Haj Kaddour, BP S/40, 50001, Meknes, Morocco.
Olive trees are susceptible to various diseases, notably root rot caused by Pythium spp., which presents significant challenges to cultivation. Conventional chemical control methods have limitations, necessitating exploration of eco-friendly alternatives like biological control strategies.
View Article and Find Full Text PDFBackground: The aim of this study was to explore the value of heparin-binding protein (HBP) in the early recognition of sepsis coagulopathy (SIC) and the prognosis of sepsis patients.
Methods: A retrospective analysis was performed for 139 patients with sepsis admitted to the Intensive Care Unit (ICU) of Hefei Third People's Hospital from April 2022 through April 2024. The clinical baseline data, disease scores [sequential organ failure (SOFA) score, acute physiology and chronic health status (APACHE II) score, and SIC score], inflammatory markers [HBP, procalcitonin (PCT), and interleukin 6 (IL-6)], coagulation-related indexes [platelet count (PLT), prothrombin time (PT), prothrombin time international normalized ratio (PT-INR), activated partial thromboplastin time (APTT), fibrinogen (Fib), and D dimer (D-D)], and the survival time and 28-day prognosis of all patients were observed.
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