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Using Inertial Measurement Units and Machine Learning to Classify Body Positions of Adults in a Hospital Bed.
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Curtin School of Allied Health, Curtin University, Perth 6102, Australia.
In hospitals, timely interventions can prevent avoidable clinical deterioration. Early recognition of deterioration is vital to stopping further decline. Measuring the way patients position themselves in bed and change their positions may signal when further assessment is necessary.
View Article and Find Full Text PDFFactors Influencing the Choice Between Multi-Target Stool DNA and Colonoscopy for Colorectal Cancer Screening Among Alaska Native Peoples.
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Alaska Native Tribal Health Consortium, 3900 Ambassador Dr., Anchorage, AK 99508, USA.
The Alaska Tribal Health System is increasing colorectal cancer (CRC) screening among Alaska Native (AN) peoples, who experience the highest CRC rate in the world. Through a clinical trial (NCT04336397), AN people living in rural/remote Alaska were offered either the previously unavailable multi-target stool DNA test (mt-sDNA; Cologuard) or colonoscopy. From April 2022 to August 2024, 113 (59%) people who completed mt-sDNA testing and 51 (39%) who completed a colonoscopy procedure participated in a survey on factors influencing their screening test choice.
View Article and Find Full Text PDFAdvancing Food Security with Farmed Edible Insects: Economic, Social, and Environmental Aspects.
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Farmed edible insects are considered a potential resource to help address food security concerns toward the year 2050. The sustainability (e.g.
View Article and Find Full Text PDFDysbiosis-NK Cell Crosstalk in Pancreatic Cancer: Toward a Unified Biomarker Signature for Improved Clinical Outcomes.
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Department of Oncology, Vejle Hospital, University Hospital of Southern Denmark, 7100 Vejle, Denmark.
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with poor prognosis, primarily due to its immunosuppressive tumor microenvironment (TME), which contributes to treatment resistance. Recent research shows that the microbiome, including microbial communities in the oral cavity, gut, bile duct, and intratumoral environments, plays a key role in PDAC development, with microbial imbalances (dysbiosis) promoting inflammation, cancer progression, therapy resistance, and treatment side effects. Microbial metabolites can also affect immune cells, especially natural killer (NK) cells, which are vital for tumor surveillance, therapy response and treatment-related side effects.
View Article and Find Full Text PDFEcological and Functional Changes in the Hindgut Microbiome of Holstein Cows at High Altitudes.
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Laboratory of Animal Genetics, Breeding and Reproduction, Ministry of Agriculture of China, National Engineering Laboratory of Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China.
The extreme environmental conditions of the Qinhai-Tibetan Plateau (QTP) challenge livestock survival and productivity, yet little is known about how high-altitude environments impact the gut microbiota of dairy cows. To fill this gap, we systematically investigated the differences in the hindgut microbiome between 87 plateau Holstein cows and 72 plain Holstein cows using 16S rRNA gene sequencing. Our analysis revealed that the hindgut microbiota of the plateau group exhibited lower species richness but higher evenness than that in the plain group.
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