A fluorescent capillary sensor for detecting the bioanalytically and biologically relevant analytes pH, O, and CO has been designed. The sensor is based on single capillary tube with 2 mm inner diameter, which is simultaneous doped with emissive O-sensitive indicator Ru(dpp)(PF6) (RuDP), pH-sensitive and CO-sensitive indicator 8-hydroxypyrene-1, 3,6-trisulfonic acid trisodium salt (HPTS). The multifunctional sensor can be excited at the same wavelength and realize multi-parameter optical monitoring at the different sensing position. Studies in phosphate-buffered solutions display the excellent feasibility of the capillary sensor for fluorescence detection of pH, O, and CO. Overall, the multifunctional capillary sensor exhibits great potential in real-time blood gas analysis, and clinical application of multi-parameter biological detection.
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| http://dx.doi.org/10.1016/j.saa.2023.123349 | DOI Listing |
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